Reaction catalyzed by steroid 21-monooxygenase (1.14.14.16)
+
[reduced NADPH-P450 reductase]
+
=
+
[oxidized NADPH-P450 reductase]
+
H2O
17alpha-hydroxyprogesterone
+
[reduced NADPH-P450 reductase]
+
O2
=
11-deoxycortisol
+
[oxidized NADPH-P450 reductase]
+
H2O
