Reaction catalyzed by vitamin D3 24-hydroxylase (1.14.15.16)
+
NADPH
+
+
=
+
+
+
+
NADP+
+
H2O
25-hydroxyvitamin D3
+
NADPH
+
H+
+
O2
=
24-oxo-25-hydroxyvitamin D3
+
23(S),25-dihydroxyvitamin D3
+
24(R),25-dihydroxyvitamin D3
+
24-oxo-23(S),25-dihydoxyvitamin D3
+
NADP+
+
H2O
