Reaction catalyzed by vitamin D3 24-hydroxylase (1.14.15.16)
+
NADPH
+
+
=
+
+
+
+
NADP+
+
H2O
1alpha,25-dihydroxyvitamin D3
+
NADPH
+
H+
+
O2
=
24-oxo-1,23,25-trihydroxyvitamin D3
+
24,25,26,27-tetranor-1,23-dihydroxyvitamin D3
+
1alpha,24R,25-trihydroxyvitamin D3
+
24-oxo-1,25-dihydroxyvitamin D3
+
NADP+
+
H2O
