Reaction catalyzed by premnaspirodiene oxygenase (1.14.14.151)
+
3
+
3
=
+
+
+
3
+
3
H2O
5-epiaristolochene
+
3 [reduced NADPH-hemoprotein reductase]
+
3 O2
=
2beta-hydroxy-5-epiaristolochene
+
1beta-hydroxy-5-epiaristolochene
+
3alpha-hydroxy-5-epiaristolochene
+
3 [oxidized NADPH-hemoprotein reductase]
+
3 H2O
