Reaction catalyzed by 2-polyprenyl-6-hydroxyphenol methylase (2.1.1.222)

		+			=			+
	S-adenosyl-L-methionine	+		3-(all-trans-octaprenyl)benzene-1,2-diol	=		S-adenosyl-L-homocysteine	+		2-methoxy-6-(all-trans-octaprenyl)phenol