Reaction catalyzed by peptide-O-fucosyltransferase (2.4.1.221)

		+		[protein]-(L-serine/L-threonine)	=			+		[protein]-3-O-(alpha-L-fucosyl)-(L-serine/L-threonine)
	GDP-beta-L-fucose	+		[protein]-(L-serine/L-threonine)	=		GDP	+		[protein]-3-O-(alpha-L-fucosyl)-(L-serine/L-threonine)