Reaction catalyzed by leukotriene-E4 20-monooxygenase (1.14.13.34)
+
NADPH
+
+
=
+
NADP+
+
H2O
(7E,9E,11Z,14Z)-(5S,6R)-6-(cystein-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate
+
NADPH
+
H+
+
O2
=
20-hydroxyleukotriene E4
+
NADP+
+
H2O
