Reaction catalyzed by heme oxygenase (biliverdin-producing) (1.14.14.18), heme oxygenase (biliverdin-IX-beta and delta-forming) (1.14.99.58)
+
3
+
3
=
+
Fe2+
+
+
3
+
3
H2O
protoheme
+
3 [reduced NADPH-hemoprotein reductase]
+
3 O2
=
biliverdin
+
Fe2+
+
CO
+
3 [oxidized NADPH-hemoprotein reductase]
+
3 H2O
