Reaction catalyzed by uracil-DNA glycosylase (3.2.2.27)
5-hydroxyuracil-mismatched single-stranded DNA
+
H2O
=
+
single-stranded DNA with abasic site
5-hydroxyuracil-mismatched single-stranded DNA
+
H2O
=
5-hydroxyuracil
+
single-stranded DNA with abasic site