Reaction catalyzed by uracil-DNA glycosylase (3.2.2.27), thymine-DNA glycosylase (3.2.2.29)

	5-hydroxymethyluracil-mismatched double-stranded DNA	+		H2O	=			+		double-stranded DNA with abasic site
	5-hydroxymethyluracil-mismatched double-stranded DNA	+		H2O	=		5-hydroxymethyluracil	+		double-stranded DNA with abasic site