Reaction catalyzed by nitric-oxide synthase (NADPH) (1.14.13.39)
2
+
3
NADPH
+
3
+
4
=
2
+
2
+
3
NADP+
+
4
H2O
2 L-arginine
+
3 NADPH
+
3 H+
+
4 O2
=
2 citrulline
+
2 nitric oxide
+
3 NADP+
+
4 H2O
