Reaction catalyzed by 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase (1.1.1.312)
+
NADP+
=
+
NADPH
+
H2O
4-carboxy-2-hydroxymuconate semialdehyde
+
NADP+
=
2-pyrone-4,6-dicarboxylic acid
+
NADPH
+
H2O
