Reaction catalyzed by phosphoinositide 5-phosphatase (3.1.3.36), inositol-polyphosphate 5-phosphatase (3.1.3.56)

		+		H2O	=			+
	1D-myo-inositol 4,5,6-trisphosphate	+		H2O	=		1D-myo-inositol 4,6-bisphosphate	+		phosphate