Reaction catalyzed by 25/26-hydroxycholesterol 7alpha-hydroxylase (1.14.14.29)
+
NADPH
+
+
=
+
NADP+
+
H2O
17beta-estradiol
+
NADPH
+
H+
+
O2
=
1,3,5(10)-estratrien-3,7-alpha,17beta-triol
+
NADP+
+
H2O
