Reaction catalyzed by hydroxymethylglutaryl-CoA reductase (NADPH) (1.1.1.34)
+
NADPH
+
=
+
CoA
+
NADP+
(S)-3-hydroxy-3-methylglutaryl-CoA
+
NADPH
+
H+
=
mevaldehyde
+
CoA
+
NADP+
