Reaction catalyzed by dihydromethanophenazine:CoB-CoM heterodisulfide reductase (1.8.98.1)

		+			=			+
	N-(7-[(2-sulfoethyl)dithio]heptanoyl)-3-O-phospho-L-threonine	+		H2	=		coenzyme B	+		coenzyme M