Reaction catalyzed by prostaglandin-E2 9-reductase (1.1.1.189)
+
NADP+
=
+
NADPH
+
(5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate
+
NADP+
=
(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate
+
NADPH
+
H+
