Reaction catalyzed by tRNA (guanosine18-2'-O)-methyltransferase (2.1.1.34)

		+			=			+		2-methylthio N6(gamma,gamma,dimethylallyl)adenosine in tRNA
	S-adenosyl-L-methionine	+		tRNA	=		S-adenosyl-L-homocysteine	+		2-methylthio N6(gamma,gamma,dimethylallyl)adenosine in tRNA