Reaction catalyzed by 2-oxoglutarate dehydrogenase system (1.2.1.105), oxoglutarate dehydrogenase (succinyl-transferring) (1.2.4.2)

		+			=			+
	2-oxoglutarate	+		[dihydrolipoyllysine-residue succinyltransferase] lipoyllysine	=		[dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine	+		CO2