Reaction catalyzed by 15-hydroxyprostaglandin-D dehydrogenase (NADP+) (1.1.1.196)
+
NADP+
=
+
NADPH
+
(5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate
+
NADP+
=
(5Z,13E)-9alpha-hydroxy-11,15-dioxoprosta-5,13-dienoate
+
NADPH
+
H+
