Reaction catalyzed by catechol O-methyltransferase (2.1.1.6)
+
=
+
+
2-hydroxyestradiol-17beta
+
S-adenosyl-L-methionine
=
2-methoxyestradiol-17beta
+
2-hydroxyestradiol-17beta methyl ether
+
S-adenosyl-L-homocysteine
