Reaction catalyzed by 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming) (1.1.1.274), 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) (1.1.1.346)
+
NADPH
+
=
+
NADP+
ethyl 2-methylacetoacetate
+
NADPH
+
H+
=
ethyl (2R)-methyl-(3S)-hydroxybutanoate
+
NADP+
