Reaction catalyzed by glutathione peroxidase (1.11.1.9), prostaglandin-E synthase (5.3.99.3)
+
2
=
+
+
H2O
5-hydroperoxyeicosatetraenoic acid
+
2 GSH
=
5-hydroxyeicosatetraenoic acid
+
GSSG
+
H2O