Reaction catalyzed by berbamunine synthase (1.14.19.66)
2
+
2
+
+
=
+
+
+
H2O
2 (S)-N-methylcoclaurine
+
2 (R)-N-methylcoclaurine
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
berbamunine
+
guattegaumerine
+
[oxidized NADPH-hemoprotein reductase]
+
H2O