Reaction catalyzed by acetate-CoA ligase (6.2.1.1), medium-chain acyl-CoA ligase (6.2.1.2), 3-(methylthio)propionyl-CoA ligase (6.2.1.44)
ATP
+
+
CoA
=
AMP
+
+
ATP
+
isobutyrate
+
CoA
=
AMP
+
diphosphate
+
isobutyryl-CoA
