Sequence of TPC1_STRAW
EC Number:4.2.3.96
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
avermitilol synthase
Q82RR7
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
335
36480
Reaction
(2E,6E)-farnesyl diphosphate + H2O = avermitilol + diphosphate
Other sequences found for EC No. 4.2.3.96
General information:
Sequence
0 MPQDIDFGLP APAGISPGLE ATRRHNLGWV RRLGLVGDGP SLAWYTSWDM PRLAACGFPH
60 ARGAALDLCA DAMAFFFVFD DQFDGPLGRD PARAARVCRR LTGIVHGAGP GPGADACSAA
120 FADVWARSTD GAHPGWVART AHEWEYYFAA QAHEAINRLR GTPGDMESYL QVRRGIAGTD
180 LPLSLGERAA GITVPAAAFH SPQLRIMREA AIDVTLMCND VYSLEKEEAR GDMDNLVLVI
240 EHARRCTRDE AVTAARGEVA RRVIRFEQLA REVPALCAQL GLSAVERAHV DTYLGVMEAW
300 MSGYHAWQTQ TRRYTGAPHV LPSTGPGYFD EVLPT
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
494098
Omura S.,Ikeda H.,Ishikawa J.,Hanamoto A.,Takahashi C.,Shinose M.,Takahashi Y.,Horikawa H.,Nakazawa H.,Osonoe T.,Kikuchi H.,Shiba T.,Sakaki Y.,Hattori M.
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.
Proc. Natl. Acad. Sci. U.S.A.
98
12215-12220
2001
494099
Ikeda H.,Ishikawa J.,Hanamoto A.,Shinose M.,Kikuchi H.,Shiba T.,Sakaki Y.,Hattori M.,Omura S.
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.
Nat. Biotechnol.
21
526-531
2003
494100
Chou W.K.,Fanizza I.,Uchiyama T.,Komatsu M.,Ikeda H.,Cane D.E.
Genome mining in Streptomyces avermitilis: cloning and characterization of SAV_76, the synthase for a new sesquiterpene, avermitilol.
J. Am. Chem. Soc.
132
8850-8851
2010
