Sequence of POLG_HCVJ8
EC Number:3.4.21.98
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
Hydrolysis of four peptide bonds in the viral precursor polyprotein, commonly with Asp or Glu in the P6 position, Cys or Thr in P1 and Ser or Ala in P1'
Other sequences found for EC No. 3.4.21.98
General information:
Sequence
0 MSTNPKPQRK TKRNTNRRPQ DVKFPGGGQI VGGVYLLPRR GPRLGVRATR KTSERSQPRG
60 RRQPIPKDRR STGKSWGKPG YPWPLYGNEG CGWAGWLLSP RGSRPTWGPT DPRHRSRNLG
120 RVIDTITCGF ADLMGYIPVV GAPVGGVARA LAHGVRVLED GINYATGNLP GCSFSIFLLA
180 LLSCVTVPVS AVEVRNISSS YYATNDCSNN SITWQLTDAV LHLPGCVPCE NDNGTLHCWI
240 QVTPNVAVKH RGALTRSLRT HVDMIVMAAT ACSALYVGDV CGAVMILSQA FMVSPQRHNF
300 TQECNCSIYQ GHITGHRMAW DMMLSWSPTL TMILAYAARV PELVLEIIFG GHWGVVFGLA
360 YFSMQGAWAK VIAILLLVAG VDATTYSSGQ EAGRTVAGFA GLFTTGAKQN LYLINTNGSW
420 HINRTALNCN DSLQTGFLAS LFYTHKFNSS GCPERLSSCR GLDDFRIGWG TLEYETNVTN
480 DGDMRPYCWH YPPRPCGIVP ARTVCGPVYC FTPSPVVVGT TDKQGVPTYT WGENETDVFL
540 LNSTRPPRGA WFGCTWMNGT GFTKTCGAPP CRIRKDYNST IDLLCPTDCF RKHPDATYLK
600 CGAGPWLTPR CLVDYPYRLW HYPCTVNFTI FKARMYVGGV EHRFSAACNF TRGDRCRLED
660 RDRGQQSPLL HSTTEWAVLP CSFSDLPALS TGLLHLHQNI VDVQYLYGLS PALTRYIVKW
720 EWVILLFLLL ADARICACLW MLIILGQAEA ALEKLIILHS ASAASANGPL WFFIFFTAAW
780 YLKGRVVPVA TYSVLGLWSF LLLVLALPQQ AYALDAAEQG ELGLAILVII SIFTLTPAYK
840 ILLSRSVWWL SYMLVLAEAQ IQQWVPPLEV RGGRDGIIWV AVILHPRLVF EVTKWLLAIL
900 GPAYLLKASL LRIPYFVRAH ALLRVCTLVK HLAGARYIQM LLITIGRWTG TYIYDHLSPL
960 STWAAQGLRD LAIAVEPVVF SPMEKKVIVW GAETVACGDI LHGLPVSARL GREVLLGPAD
1020 GYTSKGWKLL APITAYTQQT RGLLGAIVVS LTGRDKNEQA GQVQVLSSVT QTFLGTSISG
1080 VLWTVYHGAG NKTLAGPKGP VTQMYTSAEG DLVGWPSPPG TKSLDPCTCG AVDLYLVTRN
1140 ADVIPVRRKD DRRGALLSPR PLSTLKGSSG GPVLCSRGHA VGLFRAAVCA RGVAKSIDFI
1200 PVESLDVATR TPSFSDNSTP PAVPQSYQVG YLHAPTGSGK STKVPAAYAS QGYKVLVLNP
1260 SVAATLGFGA YMSKAHGINP NIRTGVRTVT TGDSITYSTY GKFIADGGCA AGAYDIIICD
1320 ECHSVDATTI LGIGTVLDQA ETAGVRLVVL ATATPPGTVT TPHSNIEEVA LGHEGEIPFY
1380 GKAIPLAFIK GGRHLIFCHS KKKCDELAAA LRGMGVNAVA YYRGLDVSVI PTQGDVVVVA
1440 TDALMTGYTG DFDSVIDCNV AVSQIVDFSL DPTFTITTQT VPQDAVSRSQ RRGRTGRGRL
1500 GVYRYVSSGE RPSGMFDSVV LCECYDAGAA WYELTPAETT VRLRAYFNTP GLPVCQDHLE
1560 FWEAVFTGLT HIDAHFLSQT KQGGENFAYL TAYQATVCAR AKAPPPSWDV MWKCLTRLKP
1620 TLTGPTPLLY RLGAVTNEVT LTHPVTKYIA TCMQADLEIM TSSWVLAGGV LAAVAAYCLA
1680 TGCISIIGRL HLNDRVVVAP DKEILYEAFD EMEECASKAA LIEEGQRMAE MLKSKIQGLL
1740 QQATRQAQDI QPAIQSSWPK LEQFWAKHMW NFISGIQYLA GLSTLPGNPA VASMMAFSAA
1800 LTSPLPTSTT ILLNIMGGWL ASQIAPPAGA TGFVVSGLVG AAVGSIGLGK ILVDVLAGYG
1860 AGISGALVAF KIMSGEKPTV EDVVNLLPAI LSPGALVVGV ICAAILRRHV GQGEGAVQWM
1920 NRLIAFASRG NHVAPTHYVV ESDASQRVTQ VLSSLTITSL LRRLHAWITE DCPVPCSGSW
1980 LQDIWDWVCS ILTDFKNWLS SKLLPKMPGI PFISCQKGYK GVWAGTGVMT TRCPCGANIS
2040 GHVRMGTMKI TGPKTCLNLW QGTFPINCYT EGPCVPKPPP NYKTAIWRVA ASEYVEVTQH
2100 GSFSYVTGLT SDNLKVPCQV PAPEFFSWVD GVQIHRFAPV PGPFFRDEVT FTVGLNSFVV
2160 GSQLPCDPEP DTEVLASMLT DPSHITAEAA ARRLARGSPP SQASSSASQL SAPSLKATCT
2220 THKTAYDCDM VDANLFMGGD VTRIESDSKV IVLDSLDSMT EVEDDREPSV PSEYLIKRRK
2280 FPPALPPWAR PDYNPVLIET WKRPGYEPPT VLGCALPPTP QTPVPPPRRR RAKVLTQDNV
2340 EGVLREMADK VLSPLQDNND SGHSTGADTG GDIVQQPSDE TAASEAGSLS SMPPLEGEPG
2400 DPDLEFEPVG SAPPSEGECE VIDSDSKSWS TVSDQEDSVI CCSMSYSWTG ALITPCGPEE
2460 EKLPINPLSN SLMRFHNKVY STTSRSASLR AKKVTFDRVQ VLDAHYDSVL QDVKRAASKV
2520 SARLLTVEEA CALTPPHSAK SRYGFGAKEV RSLSRRAVNH IRSVWEDLLE DQHTPIDTTI
2580 MAKNEVFCID PTKGGKKPAR LIVYPDLGVR VCEKMALYDI AQKLPKAIMG PSYGFQYSPA
2640 ERVDFLLKAW GSKKDPMGFS YDTRCFDSTV TERDIRTEES IYQACSLPQE ARTVIHSLTE
2700 RLYVGGPMTN SKGQSCGYRR CRASGVFTTS MGNTMTCYIK ALAACKAAGI VDPVMLVCGD
2760 DLVVISESQG NEEDERNLRA FTEAMTRYSA PPGDLPRPEY DLELITSCSS NVSVALDSRG
2820 RRRYFLTRDP TTPITRAAWE TVRHSPVNSW LGNIIQYAPT IWVRMVIMTH FFSILLAQDT
2880 LNQNLNFEMY GAVYSVNPLD LPAIIERLHG LEAFSLHTYS PHELSRVAAT LRKLGAPPLR
2940 AWKSRARAVR ASLIAQGARA AICGRYLFNW AVKTKLKLTP LPEASRLDLS GWFTVGAGGG
3000 DIYHSVSHAR PRLLLLCLLL LSVGVGIFLL PAR
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
460648
Okamoto H.,Kurai K.,Okada S.,Yamamoto K.,Lizuka H.,Tanaka T.,Fukuda S.,Tsuda F.,Mishiro S.
Full-length sequence of a hepatitis C virus genome having poor homology to reported isolates: comparative study of four distinct genotypes.
Virology
188
331-341
1992
460649
McLauchlan J.
Properties of the hepatitis C virus core protein: a structural protein that modulates cellular processes.
J. Viral Hepat.
7
2-14
2000
460650
Penin F.,Dubuisson J.,Rey F.A.,Moradpour D.,Pawlotsky J.-M.
Structural biology of hepatitis C virus.
Hepatology
39
5-19
2004
