Sequence of REBD_LENAE
EC Number:1.21.98.2
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
2 3-(7-chloroindol-3-yl)-2-iminopropanoate + H2O2 = dichlorochromopyrrolate + NH3 + 2 H2O
Other sequences found for EC No. 1.21.98.2
General information:
Sequence
0 MSVFDLPRLH FAGTATTRLP TGPRNGLVDL STHSVVMDGE RFPASRPAAE YHAYLDRVGG
60 KGTAFAGNGY FAIDAGITAV ERAAGEVDTG DLLVGRAVDV WGHYNEYLAT TFNRARIFDV
120 DPSSSWTSTV MIGQFGFGRL GRSHDVGYVF TGGVHGMQPP RWHEDGRVLH QFTVPAGEDM
180 TWFGSAADSP AAARLRELVE SGEADGLVVQ LALSDAGPAP MPHAQQWRLR GTIAPWHAGE
240 PRTCPAGRLL TPHNLTADLR GDHVSLNLIS FRPPTGISGL ELRTADTDRF IARVPADDPH
300 GVVTVPAAEG GDEALCVVGT TAAGERIVVS REREVTVHVD DASVFLEHPR GPGDSDQDAE
360 IAVRTYVRGE PAAATIHIGQ YFNPRAFPLD EHATAASATP EDLDVVALCV DGTRWSRHCV
420 ISTDENGDGR FLLRGARPGA TRLLLSAEGA TPFDGLTAAA AYDNDDSLGL WSGLASVAVR
480 VLPDHWWMDD IPRDKVTFDL LYREVFAFYE LLYSFMGEEV FSLADRFRVE THPRLIWQMC
540 DPRNRAKTYY MPPTRDLTGP QARLLLAYLR AQNSDVVVPV IEPSHTRSGT PISTRTDLVR
600 ALRHGVAIEL AVMLQYLYAA FSIPTHGAGQ ELVSRGDWTP EQLRLMCGDG GETTDGGVRG
660 SLLGVAREEM IHFLVVNNVL MAVGEPFHVP DLDFGTINDT LMVPLDFSLE ALGLGSVQRF
720 IQIEQPEGLT GAVRLGDLPV PVREAEDFHY ASLSELYGDI REGLQRVPGL FLVERGRGGG
780 EHHLFLRESV NAVHPDYQLE VDDLSSALFA IDFVTEQGEG HVLTDEDTGE ESHYDTFVRV
840 ADLLMKERLT AADTRRAQWS PAYPVARNPT VHGGGQSKEL VTSPVARELM VLFNKSYFMM
900 LQLMVQHFGG SPDASLRRSK LMNAAIDVMT GVMRPLAELL VTVPSGRHGR TAGPSFELDE
960 KPAFIPRADV ARRAISLRFR HLAESARTCA LVPDKVVRNL DFLADQFATE GPR
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
343527
Sanchez C.,Butovich I.A.,Brana A.F.,Rohr J.,Mendez C.,Salas J.A.
The biosynthetic gene cluster for the antitumor rebeccamycin: characterization and generation of indolocarbazole derivatives.
Chem. Biol.
9
519-531
2002
343528
Onaka H.,Taniguchi S.,Igarashi Y.,Furumai T.
Cloning of the staurosporine biosynthetic gene cluster from Streptomyces sp. TP-A0274 and its heterologous expression in Streptomyces lividans.
J. Antibiot.
55
1063-1071
2002
343530
Onaka H.,Taniguchi S.,Igarashi Y.,Furumai T.
Characterization of the biosynthetic gene cluster of rebeccamycin from Lechevalieria aerocolonigenes ATCC 39243.
Biosci. Biotechnol. Biochem.
67
127-138
2003
343531
Onaka H.,Taniguchi S.,Ikeda H.,Igarashi Y.,Furumai T.
pTOYAMAcos, pTYM18, and pTYM19, actinomycete-Escherichia coli integrating vectors for heterologous gene expression.
J. Antibiot.
56
950-956
2003
343532
Nishizawa T.,Aldrich C.C.,Sherman D.H.
Molecular analysis of the rebeccamycin L-amino acid oxidase from Lechevalieria aerocolonigenes ATCC 39243.
J. Bacteriol.
187
2084-2092
2005
343535
Howard-Jones A.R.,Walsh C.T.
Enzymatic generation of the chromopyrrolic acid scaffold of rebeccamycin by the tandem action of RebO and RebD.
Biochemistry
44
15652-15663
2005
343536
Spolitak T.,Ballou D.P.
Evidence for catalytic intermediates involved in generating the chromopyrrolic acid scaffold of rebeccamycin by RebO and RebD.
Arch. Biochem. Biophys.
573
111-119
2015
