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Sequence of HCD2_MOUSE

EC Number:1.1.1.159

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
7alpha-hydroxysteroid dehydrogenase
O08756
Mus musculus
261
27419
Reaction
cholate + NAD+ = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholan-24-oate + NADH + H+
Other sequences found for EC No. 1.1.1.159

General information:

Sequence
show sequence in fasta format
  0 MAAAVRSVKG LVAVVTGGAS GPWLATAKRL VGQGATAVLL DVPDSEGESQ AKKLGESCIF
 60 APANVTSEKE IQAALTLAKE KFGRIDVAVN CAGIAVAIKT YHQKKNKIHT LEDFQRVINV
120 NLIGTFNVIR LVAGEMGQNE PDQGGQRGVI INTASVAAFE GQVGQAAYSA SKGGIDGMTL
180 PIARDLAPTG IRVVTIAPGL FATPLLTTLP EKVRNFLASQ VPFPSRLGDP AEYAHLVQTI
240 IENPFLNGEV IRLDGAIRMQ P
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
170796
Huttlin E.L.,Jedrychowski M.P.,Elias J.E.,Goswami T.,Rad R.,Beausoleil S.A.,Villen J.,Haas W.,Sowa M.E.,Gygi S.P.
A tissue-specific atlas of mouse protein phosphorylation and expression.
Cell
143
1174-1189
2010
170797
Rauschenberger K.,Schoeler K.,Sass J.O.,Sauer S.,Djuric Z.,Rumig C.,Wolf N.I.,Okun J.G.,Koelker S.,Schwarz H.,Fischer C.,Grziwa B.,Runz H.,Nuemann A.,Shafqat N.,Kavanagh K.L.,Haemmerling G.,Wanders R.J.,Shield J.P.,Wendel U.,Stern D.,Nawroth P.,Hoffmann G.F.,Bartram C.R.,Arnold B.,Bierhaus A.,Oppermann U.,Steinbeisser H.,Zschocke J.
A non-enzymatic function of 17beta-hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival.
EMBO Mol. Med.
2
51-62
2010
170798
Park J.,Chen Y.,Tishkoff D.X.,Peng C.,Tan M.,Dai L.,Xie Z.,Zhang Y.,Zwaans B.M.,Skinner M.E.,Lombard D.B.,Zhao Y.
SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.
Mol. Cell
50
919-930
2013
170799
Rardin M.J.,Newman J.C.,Held J.M.,Cusack M.P.,Sorensen D.J.,Li B.,Schilling B.,Mooney S.D.,Kahn C.R.,Verdin E.,Gibson B.W.
Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
Proc. Natl. Acad. Sci. U.S.A.
110
6601-6606
2013