Sequence of TRMY_METJA
EC Number:2.1.1.257
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
tRNA (pseudouridine54-N1)-methyltransferase
Q59034
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
205
23704
Reaction
S-adenosyl-L-methionine + pseudouridine54 in tRNA = S-adenosyl-L-homocysteine + N1-methylpseudouridine54 in tRNA
Other sequences found for EC No. 2.1.1.257
General information:
Sequence
0 MREFIFKANK TITSSDINLK DLPGSCGRLD LLCRCVSDAF FLSHDIRRDV VFYAVLYGQP
60 NPPVCIKFVG SELKKVSPDE RNIAIFIKKA LKKFEELDEE QRKDWNQSTP GIYVRRLGFR
120 NLVLEKLEEG KNIYYLHMNG EDVENVDIEN PVFIIGDHIG IGEEDERFLD EIKAKRISLS
180 PLELHANHCI TIIHNVLDKK RICEI
Download this sequence
Download all sequences for 2.1.1.257
Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
111869
Bult C.J.,White O.,Olsen G.J.,Zhou L.,Fleischmann R.D.,Sutton G.G.,Blake J.A.,FitzGerald L.M.,Clayton R.A.,Gocayne J.D.,Kerlavage A.R.,Dougherty B.A.,Tomb J.-F.,Adams M.D.,Reich C.I.,Overbeek R.,Kirkness E.F.,Weinstock K.G.,Merrick J.M.,Glodek A.,Scott J.L.,Geoghagen N.S.M.,Weidman J.F.,Fuhrmann J.L.,Nguyen D.,Utterback T.R.,Kelley J.M.,Peterson J.D.,Sadow P.W.,Hanna M.C.,Cotton M.D.,Roberts K.M.,Hurst M.A.,Kaine B.P.,Borodovsky M.,Klenk H.-P.,Fraser C.M.,Smith H.O.,Woese C.R.,Venter J.C.
Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii.
Science
273
1058-1073
1996
111870
Wurm J.P.,Griese M.,Bahr U.,Held M.,Heckel A.,Karas M.,Soppa J.,Woehnert J.
Identification of the enzyme responsible for N1-methylation of pseudouridine 54 in archaeal tRNAs.
RNA
18
412-420
2012
111871
Chatterjee K.,Blaby I.K.,Thiaville P.C.,Majumder M.,Grosjean H.,Yuan Y.A.,Gupta R.,de Crecy-Lagard V.
The archaeal COG1901/DUF358 SPOUT-methyltransferase members, together with pseudouridine synthase Pus10, catalyze the formation of 1-methylpseudouridine at position 54 of tRNA.
RNA
18
421-433
2012
111872
Chen H.Y.,Yuan Y.A.
Crystal structure of Mj1640/DUF358 protein reveals a putative SPOUT-class RNA methyltransferase.
J. Mol. Cell Biol.
2
366-374
2010