Sequence of HYES_MOUSE
EC Number:3.1.3.76
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
(9S,10S)-10-hydroxy-9-(phosphooxy)octadecanoate + H2O = (9S,10S)-9,10-dihydroxyoctadecanoate + phosphate
Other sequences found for EC No. 3.1.3.76
General information:
Sequence
0 MALRVAAFDL DGVLALPSIA GAFRRSEEAL ALPRDFLLGA YQTEFPEGPT EQLMKGKITF
60 SQWVPLMDES YRKSSKACGA NLPENFSISQ IFSQAMAARS INRPMLQAAI ALKKKGFTTC
120 IVTNNWLDDG DKRDSLAQMM CELSQHFDFL IESCQVGMIK PEPQIYNFLL DTLKAKPNEV
180 VFLDDFGSNL KPARDMGMVT ILVHNTASAL RELEKVTGTQ FPEAPLPVPC NPNDVSHGYV
240 TVKPGIRLHF VEMGSGPALC LCHGFPESWF SWRYQIPALA QAGFRVLAID MKGYGDSSSP
300 PEIEEYAMEL LCKEMVTFLD KLGIPQAVFI GHDWAGVMVW NMALFYPERV RAVASLNTPF
360 MPPDPDVSPM KVIRSIPVFN YQLYFQEPGV AEAELEKNMS RTFKSFFRAS DETGFIAVHK
420 ATEIGGILVN TPEDPNLSKI TTEEEIEFYI QQFKKTGFRG PLNWYRNTER NWKWSCKGLG
480 RKILVPALMV TAEKDIVLRP EMSKNMEKWI PFLKRGHIED CGHWTQIEKP TEVNQILIKW
540 LQTEVQNPSV TSKI
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
940460
Grant D.F.,Storms D.H.,Hammock B.D.
Molecular cloning and expression of murine liver soluble epoxide hydrolase.
J. Biol. Chem.
268
17628-17633
1993
940461
Johansson C.,Stark A.,Sandberg M.,Ek B.,Rask L.,Meijer J.
Tissue specific basal expression of soluble murine epoxide hydrolase and effects of clofibrate on the mRNA levels in extrahepatic tissues and liver.
Arch. Toxicol.
70
61-63
1995
940462
Hennebold J.D.,Mah K.,Perez W.,Vance J.E.,Stouffer R.L.,Morisseau C.,Hammock B.D.,Adashi E.Y.
Identification and characterization of an ovary-selective isoform of epoxide hydrolase.
Biol. Reprod.
72
968-975
2005
940463
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
940464
Zeldin D.C.,Wei S.,Falck J.R.,Hammock B.D.,Snapper J.R.,Capdevila J.H.
Metabolism of epoxyeicosatrienoic acids by cytosolic epoxide hydrolase: substrate structural determinants of asymmetric catalysis.
Arch. Biochem. Biophys.
316
443-451
1995
940465
Villen J.,Beausoleil S.A.,Gerber S.A.,Gygi S.P.
Large-scale phosphorylation analysis of mouse liver.
Proc. Natl. Acad. Sci. U.S.A.
104
1488-1493
2007
940466
Huttlin E.L.,Jedrychowski M.P.,Elias J.E.,Goswami T.,Rad R.,Beausoleil S.A.,Villen J.,Haas W.,Sowa M.E.,Gygi S.P.
A tissue-specific atlas of mouse protein phosphorylation and expression.
Cell
143
1174-1189
2010
940467
Cronin A.,Decker M.,Arand M.
Mammalian soluble epoxide hydrolase is identical to liver hepoxilin hydrolase.
J. Lipid Res.
52
712-719
2011
940468
Park J.,Chen Y.,Tishkoff D.X.,Peng C.,Tan M.,Dai L.,Xie Z.,Zhang Y.,Zwaans B.M.,Skinner M.E.,Lombard D.B.,Zhao Y.
SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.
Mol. Cell
50
919-930
2013
940469
Rardin M.J.,Newman J.C.,Held J.M.,Cusack M.P.,Sorensen D.J.,Li B.,Schilling B.,Mooney S.D.,Kahn C.R.,Verdin E.,Gibson B.W.
Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
Proc. Natl. Acad. Sci. U.S.A.
110
6601-6606
2013
940470
Argiriadi M.A.,Morisseau C.,Hammock B.D.,Christianson D.W.
Detoxification of environmental mutagens and carcinogens: structure, mechanism, and evolution of liver epoxide hydrolase.
Proc. Natl. Acad. Sci. U.S.A.
96
10637-10642
1999
940471
Argiriadi M.A.,Morisseau C.,Goodrow M.H.,Dowdy D.L.,Hammock B.D.,Christianson D.W.
Binding of alkylurea inhibitors to epoxide hydrolase implicates active site tyrosines in substrate activation.
J. Biol. Chem.
275
15265-15270
2000
