Sequence of NSUN2_MOUSE

tRNA (cytosine34-C5)-methyltransferase

Q1HFZ0

757

85452

833661

Frye M.,Watt F.M.

The RNA methyltransferase Misu (NSun2) mediates Myc-induced proliferation and is upregulated in tumors.

Curr. Biol.

16

971-981

2006

833662

Carninci P.,Kasukawa T.,Katayama S.,Gough J.,Frith M.C.,Maeda N.,Oyama R.,Ravasi T.,Lenhard B.,Wells C.,Kodzius R.,Shimokawa K.,Bajic V.B.,Brenner S.E.,Batalov S.,Forrest A.R.,Zavolan M.,Davis M.J.,Wilming L.G.,Aidinis V.,Allen J.E.,Ambesi-Impiombato A.,Apweiler R.,Aturaliya R.N.,Bailey T.L.,Bansal M.,Baxter L.,Beisel K.W.,Bersano T.,Bono H.,Chalk A.M.,Chiu K.P.,Choudhary V.,Christoffels A.,Clutterbuck D.R.,Crowe M.L.,Dalla E.,Dalrymple B.P.,de Bono B.,Della Gatta G.,di Bernardo D.,Down T.,Engstrom P.,Fagiolini M.,Faulkner G.,Fletcher C.F.,Fukushima T.,Furuno M.,Futaki S.,Gariboldi M.,Georgii-Hemming P.,Gingeras T.R.,Gojobori T.,Green R.E.,Gustincich S.,Harbers M.,Hayashi Y.,Hensch T.K.,Hirokawa N.,Hill D.,Huminiecki L.,Iacono M.,Ikeo K.,Iwama A.,Ishikawa T.,Jakt M.,Kanapin A.,Katoh M.,Kawasawa Y.,Kelso J.,Kitamura H.,Kitano H.,Kollias G.,Krishnan S.P.,Kruger A.,Kummerfeld S.K.,Kurochkin I.V.,Lareau L.F.,Lazarevic D.,Lipovich L.,Liu J.,Liuni S.,McWilliam S.,Madan Babu M.,Madera M.,Marchionni L.,Matsuda H.,Matsuzawa S.,Miki H.,Mignone F.,Miyake S.,Morris K.,Mottagui-Tabar S.,Mulder N.,Nakano N.,Nakauchi H.,Ng P.,Nilsson R.,Nishiguchi S.,Nishikawa S.,Nori F.,Ohara O.,Okazaki Y.,Orlando V.,Pang K.C.,Pavan W.J.,Pavesi G.,Pesole G.,Petrovsky N.,Piazza S.,Reed J.,Reid J.F.,Ring B.Z.,Ringwald M.,Rost B.,Ruan Y.,Salzberg S.L.,Sandelin A.,Schneider C.,Schoenbach C.,Sekiguchi K.,Semple C.A.,Seno S.,Sessa L.,Sheng Y.,Shibata Y.,Shimada H.,Shimada K.,Silva D.,Sinclair B.,Sperling S.,Stupka E.,Sugiura K.,Sultana R.,Takenaka Y.,Taki K.,Tammoja K.,Tan S.L.,Tang S.,Taylor M.S.,Tegner J.,Teichmann S.A.,Ueda H.R.,van Nimwegen E.,Verardo R.,Wei C.L.,Yagi K.,Yamanishi H.,Zabarovsky E.,Zhu S.,Zimmer A.,Hide W.,Bult C.,Grimmond S.M.,Teasdale R.D.,Liu E.T.,Brusic V.,Quackenbush J.,Wahlestedt C.,Mattick J.S.,Hume D.A.,Kai C.,Sasaki D.,Tomaru Y.,Fukuda S.,Kanamori-Katayama M.,Suzuki M.,Aoki J.,Arakawa T.,Iida J.,Imamura K.,Itoh M.,Kato T.,Kawaji H.,Kawagashira N.,Kawashima T.,Kojima M.,Kondo S.,Konno H.,Nakano K.,Ninomiya N.,Nishio T.,Okada M.,Plessy C.,Shibata K.,Shiraki T.,Suzuki S.,Tagami M.,Waki K.,Watahiki A.,Okamura-Oho Y.,Suzuki H.,Kawai J.,Hayashizaki Y.

The transcriptional landscape of the mammalian genome.

Science

309

1559-1563

2005

833663

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

Genome Res.

14

2121-2127

2004

833664

Ballif B.A.,Villen J.,Beausoleil S.A.,Schwartz D.,Gygi S.P.

Phosphoproteomic analysis of the developing mouse brain.

Mol. Cell. Proteomics

3

1093-1101

2004

833665

Villen J.,Beausoleil S.A.,Gerber S.A.,Gygi S.P.

Large-scale phosphorylation analysis of mouse liver.

Proc. Natl. Acad. Sci. U.S.A.

104

1488-1493

2007

833666

Trost M.,English L.,Lemieux S.,Courcelles M.,Desjardins M.,Thibault P.

The phagosomal proteome in interferon-gamma-activated macrophages.

Immunity

30

143-154

2009

833667

Hussain S.,Benavente S.B.,Nascimento E.,Dragoni I.,Kurowski A.,Gillich A.,Humphreys P.,Frye M.

The nucleolar RNA methyltransferase Misu (NSun2) is required for mitotic spindle stability.

J. Cell Biol.

186

27-40

2009

833668

Huttlin E.L.,Jedrychowski M.P.,Elias J.E.,Goswami T.,Rad R.,Beausoleil S.A.,Villen J.,Haas W.,Sowa M.E.,Gygi S.P.

A tissue-specific atlas of mouse protein phosphorylation and expression.

Cell

143

1174-1189

2010

833669

Blanco S.,Kurowski A.,Nichols J.,Watt F.M.,Benitah S.A.,Frye M.

The RNA-methyltransferase Misu (NSun2) poises epidermal stem cells to differentiate.

PLoS Genet.

7

0-0

2011

833670

Tuorto F.,Liebers R.,Musch T.,Schaefer M.,Hofmann S.,Kellner S.,Frye M.,Helm M.,Stoecklin G.,Lyko F.

RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis.

Nat. Struct. Mol. Biol.

19

900-905

2012

833671

Hussain S.,Sajini A.A.,Blanco S.,Dietmann S.,Lombard P.,Sugimoto Y.,Paramor M.,Gleeson J.G.,Odom D.T.,Ule J.,Frye M.

NSun2-mediated cytosine-5 methylation of vault noncoding RNA determines its processing into regulatory small RNAs.

Cell Rep.

4

255-261

2013

833672

Hussain S.,Tuorto F.,Menon S.,Blanco S.,Cox C.,Flores J.V.,Watt S.,Kudo N.R.,Lyko F.,Frye M.

The mouse cytosine-5 RNA methyltransferase NSun2 is a component of the chromatoid body and required for testis differentiation.

Mol. Cell. Biol.

33

1561-1570

2013

833673

Park J.,Chen Y.,Tishkoff D.X.,Peng C.,Tan M.,Dai L.,Xie Z.,Zhang Y.,Zwaans B.M.,Skinner M.E.,Lombard D.B.,Zhao Y.

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

Mol. Cell

50

919-930

2013

833674

Kossinova O.A.,Gopanenko A.V.,Tamkovich S.N.,Krasheninina O.A.,Tupikin A.E.,Kiseleva E.,Yanshina D.D.,Malygin A.A.,Ven'yaminova A.G.,Kabilov M.R.,Karpova G.G.

Cytosolic YB-1 and NSUN2 are the only proteins recognizing specific motifs present in mRNAs enriched in exosomes.

Biochim. Biophys. Acta

1865

664-673

2017

833675

Van Haute L.,Lee S.Y.,McCann B.J.,Powell C.A.,Bansal D.,Vasiliauskaite L.,Garone C.,Shin S.,Kim J.S.,Frye M.,Gleeson J.G.,Miska E.A.,Rhee H.W.,Minczuk M.

NSUN2 introduces 5-methylcytosines in mammalian mitochondrial tRNAs.

Nucleic Acids Res.

47

8720-8733

2019

833676

Shinoda S.,Kitagawa S.,Nakagawa S.,Wei F.Y.,Tomizawa K.,Araki K.,Araki M.,Suzuki T.,Suzuki T.

Mammalian NSUN2 introduces 5-methylcytidines into mitochondrial tRNAs.

Nucleic Acids Res.

47

8734-8745

2019

833677

Gkatza N.A.,Castro C.,Harvey R.F.,Heiss M.,Popis M.C.,Blanco S.,Borneloev S.,Sajini A.A.,Gleeson J.G.,Griffin J.L.,West J.A.,Kellner S.,Willis A.E.,Dietmann S.,Frye M.

Cytosine-5 RNA methylation links protein synthesis to cell metabolism.

PLoS Biol.

17

0-0

2019