Sequence of SIDA_ASPFU

L-ornithine N5-monooxygenase [NAD(P)H]

E9QYP0

501

56877

737018

Schrettl M.,Bignell E.,Kragl C.,Joechl C.,Rogers T.,Arst H.N. Jr.,Haynes K.,Haas H.

Siderophore biosynthesis but not reductive iron assimilation is essential for Aspergillus fumigatus virulence.

J. Exp. Med.

200

1213-1219

2004

737019

Hissen A.H.,Wan A.N.,Warwas M.L.,Pinto L.J.,Moore M.M.

The Aspergillus fumigatus siderophore biosynthetic gene sidA, encoding L-ornithine N(5)-oxygenase, is required for virulence.

Infect. Immun.

73

5493-5503

2005

737020

Nierman W.C.,Pain A.,Anderson M.J.,Wortman J.R.,Kim H.S.,Arroyo J.,Berriman M.,Abe K.,Archer D.B.,Bermejo C.,Bennett J.W.,Bowyer P.,Chen D.,Collins M.,Coulsen R.,Davies R.,Dyer P.S.,Farman M.L.,Fedorova N.,Fedorova N.D.,Feldblyum T.V.,Fischer R.,Fosker N.,Fraser A.,Garcia J.L.,Garcia M.J.,Goble A.,Goldman G.H.,Gomi K.,Griffith-Jones S.,Gwilliam R.,Haas B.J.,Haas H.,Harris D.E.,Horiuchi H.,Huang J.,Humphray S.,Jimenez J.,Keller N.,Khouri H.,Kitamoto K.,Kobayashi T.,Konzack S.,Kulkarni R.,Kumagai T.,Lafton A.,Latge J.-P.,Li W.,Lord A.,Lu C.,Majoros W.H.,May G.S.,Miller B.L.,Mohamoud Y.,Molina M.,Monod M.,Mouyna I.,Mulligan S.,Murphy L.D.,O'Neil S.,Paulsen I.,Penalva M.A.,Pertea M.,Price C.,Pritchard B.L.,Quail M.A.,Rabbinowitsch E.,Rawlins N.,Rajandream M.A.,Reichard U.,Renauld H.,Robson G.D.,Rodriguez de Cordoba S.,Rodriguez-Pena J.M.,Ronning C.M.,Rutter S.,Salzberg S.L.,Sanchez M.,Sanchez-Ferrero J.C.,Saunders D.,Seeger K.,Squares R.,Squares S.,Takeuchi M.,Tekaia F.,Turner G.,Vazquez de Aldana C.R.,Weidman J.,White O.,Woodward J.R.,Yu J.-H.,Fraser C.M.,Galagan J.E.,Asai K.,Machida M.,Hall N.,Barrell B.G.,Denning D.W.

Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus.

Nature

438

1151-1156

2005

737021

Schrettl M.,Bignell E.,Kragl C.,Sabiha Y.,Loss O.,Eisendle M.,Wallner A.,Arst H.N. Jr.,Haynes K.,Haas H.

Distinct roles for intra- and extracellular siderophores during Aspergillus fumigatus infection.

PLoS Pathog.

3

1195-1207

2007

737022

Schrettl M.,Kim H.S.,Eisendle M.,Kragl C.,Nierman W.C.,Heinekamp T.,Werner E.R.,Jacobsen I.,Illmer P.,Yi H.,Brakhage A.A.,Haas H.

SreA-mediated iron regulation in Aspergillus fumigatus.

Mol. Microbiol.

70

27-43

2008

737023

Chocklett S.W.,Sobrado P.

Aspergillus fumigatus SidA is a highly specific ornithine hydroxylase with bound flavin cofactor.

Biochemistry

49

6777-6783

2010

737024

Mayfield J.A.,Frederick R.E.,Streit B.R.,Wencewicz T.A.,Ballou D.P.,DuBois J.L.

Comprehensive spectroscopic, steady state, and transient kinetic studies of a representative siderophore-associated flavin monooxygenase.

J. Biol. Chem.

285

30375-30388

2010

737025

Blatzer M.,Schrettl M.,Sarg B.,Lindner H.H.,Pfaller K.,Haas H.

SidL, an Aspergillus fumigatus transacetylase involved in biosynthesis of the siderophores ferricrocin and hydroxyferricrocin.

Appl. Environ. Microbiol.

77

4959-4966

2011

737026

Romero E.,Fedkenheuer M.,Chocklett S.W.,Qi J.,Oppenheimer M.,Sobrado P.

Dual role of NADP(H) in the reaction of a flavin dependent N-hydroxylating monooxygenase.

Biochim. Biophys. Acta

1824

850-857

2012

737027

Yasmin S.,Alcazar-Fuoli L.,Gruendlinger M.,Puempel T.,Cairns T.,Blatzer M.,Lopez J.F.,Grimalt J.O.,Bignell E.,Haas H.

Mevalonate governs interdependency of ergosterol and siderophore biosyntheses in the fungal pathogen Aspergillus fumigatus.

Proc. Natl. Acad. Sci. U.S.A.

109

0-0

2012

737028

Franceschini S.,Fedkenheuer M.,Vogelaar N.J.,Robinson H.H.,Sobrado P.,Mattevi A.

Structural insight into the mechanism of oxygen activation and substrate selectivity of flavin-dependent N-hydroxylating monooxygenases.

Biochemistry

51

7043-7045

2012