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Sequence of MTD_METKA

EC Number:1.5.98.1

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
methylenetetrahydromethanopterin dehydrogenase
P94951
Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
283
31382
Reaction
5,10-methylenetetrahydromethanopterin + oxidized coenzyme F420 + H+ = 5,10-methenyltetrahydromethanopterin + reduced coenzyme F420
Other sequences found for EC No. 1.5.98.1

General information:

Sequence
show sequence in fasta format
  0 MTVAKAIFIK CGNLGTSMMM DMLLDERADR EDVEFRVVGT SVKMDPECVE AAVEMALDIA
 60 EDFEPDFIVY GGPNPAAPGP SKAREMLADS EYPAVIIGDA PGLKVKDEME EQGLGYILVK
120 PDAMLGARRE FLDPVEMAIY NADLMKVLAA TGVFRVVQEA FDELIEKAKE DEISENDLPK
180 LVIDRNTLLE REEFENPYAM VKAMAALEIA ENVADVSVEG CFVEQDKERY VPIVASAHEM
240 MRKAAELADE ARELEKSNDA VLRTPHAPDG KVLSKRKFME DPE
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
572438
Klein A.R.,Thauer R.K.
Overexpression of the coenzyme-F420-dependent N5,N10-methylenetetrahydromethanopterin dehydrogenase gene from the hyperthermophilic Methanopyrus kandleri.
Eur. J. Biochem.
245
386-391
1997
572439
Slesarev A.I.,Mezhevaya K.V.,Makarova K.S.,Polushin N.N.,Shcherbinina O.V.,Shakhova V.V.,Belova G.I.,Aravind L.,Natale D.A.,Rogozin I.B.,Tatusov R.L.,Wolf Y.I.,Stetter K.O.,Malykh A.G.,Koonin E.V.,Kozyavkin S.A.
The complete genome of hyperthermophile Methanopyrus kandleri AV19 and monophyly of archaeal methanogens.
Proc. Natl. Acad. Sci. U.S.A.
99
4644-4649
2002
572440
Klein A.R.,Koch J.,Stetter K.O.,Thauer R.K.
Two N5,N10-methylenetetrahydromethanopterin dehydrogenases in the extreme thermophile Methanopyrus kandleri: characterization of the coenzyme F420-dependent enzyme.
Arch. Microbiol.
160
186-192
1993
572441
Hagemeier C.H.,Shima S.,Warkentin E.,Thauer R.K.,Ermler U.
Coenzyme F420-dependent methylenetetrahydromethanopterin dehydrogenase from Methanopyrus kandleri: the selenomethionine-labelled and non-labelled enzyme crystallized in two different forms.
Acta Crystallogr. D
59
1653-1655
2003
572442
Hagemeier C.H.,Shima S.,Thauer R.K.,Bourenkov G.,Bartunik H.D.,Ermler U.
Coenzyme F420-dependent methylenetetrahydromethanopterin dehydrogenase (Mtd) from Methanopyrus kandleri: a methanogenic enzyme with an unusual quarternary structure.
J. Mol. Biol.
332
1047-1057
2003