Sequence of FMO3_HUMAN

trimethylamine monooxygenase

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Dolphin C.T.,Riley J.H.,Smith R.L.,Shephard E.A.,Phillips I.R.

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The DNA sequence and biological annotation of human chromosome 1.

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The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

Genome Res.

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2004

544916

Haining R.L.,Hunter A.P.,Sadeque A.J.,Philpot R.M.,Rettie A.E.

Baculovirus-mediated expression and purification of human FMO3: catalytic, immunochemical, and structural characterization.

Drug Metab. Dispos.

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1997

544917

Lang D.H.,Yeung C.K.,Peter R.M.,Ibarra C.,Gasser R.,Itagaki K.,Philpot R.M.,Rettie A.E.

Isoform specificity of trimethylamine N-oxygenation by human flavin-containing monooxygenase (FMO) and P450 enzymes: selective catalysis by FMO3.

Biochem. Pharmacol.

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1998

544918

Treacy E.P.,Akerman B.R.,Chow L.M.L.,Youil R.,Bibeau C.,Lin J.,Bruce A.G.,Knight M.,Danks D.M.,Cashman J.R.,Forrest S.M.

Mutations of the flavin-containing monooxygenase gene (FMO3) cause trimethylaminuria, a defect in detoxication.

Hum. Mol. Genet.

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1998

544919

Rawden H.C.,Kokwaro G.O.,Ward S.A.,Edwards G.

Relative contribution of cytochromes P-450 and flavin-containing monooxygenases to the metabolism of albendazole by human liver microsomes.

Br. J. Clin. Pharmacol.

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2000

544920

Yeung C.K.,Adman E.T.,Rettie A.E.

Functional characterization of genetic variants of human FMO3 associated with trimethylaminuria.

Arch. Biochem. Biophys.

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2007

544921

Bian Y.,Song C.,Cheng K.,Dong M.,Wang F.,Huang J.,Sun D.,Wang L.,Ye M.,Zou H.

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

J. Proteomics

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2014

544922

Zhu W.,Buffa J.A.,Wang Z.,Warrier M.,Schugar R.,Shih D.M.,Gupta N.,Gregory J.C.,Org E.,Fu X.,Li L.,DiDonato J.A.,Lusis A.J.,Brown J.M.,Hazen S.L.

Flavin monooxygenase 3, the host hepatic enzyme in the metaorganismal trimethylamine N-oxide-generating pathway, modulates platelet responsiveness and thrombosis risk.

J. Thromb. Haemost.

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2018

544923

Perez-Paramo Y.X.,Chen G.,Ashmore J.H.,Watson C.J.W.,Nasrin S.,Adams-Haduch J.,Wang R.,Gao Y.T.,Koh W.P.,Yuan J.M.,Lazarus P.

Nicotine-N'-oxidation by flavin monooxygenase enzymes.

Cancer Epidemiol. Biomarkers Prev.

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311-320

2019

544924

Akerman B.R.,Forrest S.M.,Chow L.M.L.,Youil R.,Knight M.,Treacy E.P.

Two novel mutations of the FMO3 gene in a proband with trimethylaminuria.

Hum. Mutat.

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376-379

1999

544925

Akerman B.R.,Lemass H.,Chow L.M.L.,Lambert D.M.,Greenberg C.,Bibeau C.,Mamer O.A.,Treacy E.P.

Trimethylaminuria is caused by mutations of the FMO3 gene in a North American cohort.

Mol. Genet. Metab.

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24-31

1999

544926

Dolphin C.T.,Janmohamed A.,Smith R.L.,Shephard E.A.,Phillips I.R.

Compound heterozygosity for missense mutations in the flavin-containing monooxygenase 3 (FM03) gene in patients with fish-odour syndrome.

Pharmacogenetics

10

799-807

2000

544927

Furnes B.,Feng J.,Sommer S.S.,Schlenk D.

Identification of novel variants of the flavin-containing monooxygenase gene family in African Americans.

Drug Metab. Dispos.

31

187-193

2003

544928

Fujieda M.,Yamazaki H.,Togashi M.,Saito T.,Kamataki T.

Two novel single nucleotide polymorphisms (SNPs) of the FMO3 gene in Japanese.

Drug Metab. Pharmacokinet.

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333-335

2003

544929

Zhang J.,Tran Q.,Lattard V.,Cashman J.R.

Deleterious mutations in the flavin-containing monooxygenase 3 (FMO3) gene causing trimethylaminuria.

Pharmacogenetics

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495-500

2003

544930

Koukouritaki S.B.,Poch M.T.,Henderson M.C.,Siddens L.K.,Krueger S.K.,VanDyke J.E.,Williams D.E.,Pajewski N.M.,Wang T.,Hines R.N.

Identification and functional analysis of common human flavin-containing monooxygenase 3 genetic variants.

J. Pharmacol. Exp. Ther.

320

266-273

2007