Sequence of ELMGT_STROV
EC Number:2.4.1.331
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
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Reaction
dTDP-beta-L-rhamnose + 8-demethyltetracenomycin C = dTDP + 8-demethyl-8-alpha-L-rhamnosyltetracenomycin C
Other sequences found for EC No. 2.4.1.331
General information:
Sequence
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>Q9F2F9|8-demethyltetracenomycin C L-rhamnosyltransferase|EC 2.4.1.331|Streptomyces olivaceus|Swiss-Prot
MRVLAVATPALGHLFPAVPLLWALRARGDEVLVVTGGDALRVAEAGLPVVDALPGETLTT
LFGAYQETDPAFFVALRRSPMTTLRDLAPVLAYLAGRLLEPARRAAERWRPDAILATHGQ
AAGAVVAAEHGIPLVEHGFGFVRSDGAQEAVRQLLAERLGPAGSEPPPERYFLDIAVPSM
TSAIEGMSLRAVPYNGGAVLPLSGASVGGRPPRPRVLVTAGTQLLHTHGAGALAWLPEVA
AGHEAEFLLAAGGADLRDLGRLPPHVRVLDWTPLATVLPTCSAVVHHGGSGTTLAALAAG
VPQLVSPALADNHINARAVADRGAGLETAVPDATTLTALLREPAFAKAAREVADELRSLP
APADVAARLHTAFGLPTTQGDA
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
540043
Blanco G.,Patallo E.P.,Brana A.F.,Trefzer A.,Bechthold A.,Rohr J.,Mendez C.,Salas J.A.
Identification of a sugar flexible glycosyltransferase from Streptomyces olivaceus, the producer of the antitumor polyketide elloramycin.
Chem. Biol.
8
253-263
2001
540044
Patallo E.P.,Blanco G.,Fischer C.,Brana A.F.,Rohr J.,Mendez C.,Salas J.A.
Deoxysugar methylation during biosynthesis of the antitumor polyketide elloramycin by Streptomyces olivaceus. Characterization of three methyltransferase genes.
J. Biol. Chem.
276
18765-18774
2001
540045
Ramos A.,Lombo F.,Brana A.F.,Rohr J.,Mendez C.,Salas J.A.
Biosynthesis of elloramycin in Streptomyces olivaceus requires glycosylation by enzymes encoded outside the aglycon cluster.
Microbiology
154
781-788
2008
540046
Fischer C.,Rodriguez L.,Patallo E.P.,Lipata F.,Brana A.F.,Mendez C.,Salas J.A.,Rohr J.
Digitoxosyltetracenomycin C and glucosyltetracenomycin C, two novel elloramycin analogues obtained by exploring the sugar donor substrate specificity of glycosyltransferase ElmGT.
J. Nat. Prod.
65
1685-1689
2002
540047
Ramos A.,Olano C.,Brana A.F.,Mendez C.,Salas J.A.
Modulation of deoxysugar transfer by the elloramycin glycosyltransferase ElmGT through site-directed mutagenesis.
J. Bacteriol.
191
2871-2875
2009
