Sequence of IKKA_MOUSE

IkappaB kinase

Q60680

745

84729

47116

Mock B.A.,Connelly M.A.,McBride O.W.,Kozak C.A.,Marcu K.B.

CHUK, a conserved helix-loop-helix ubiquitous kinase, maps to human chromosome 10 and mouse chromosome 19.

Genomics

27

348-351

1995

47117

Connelly M.A.,Marcu K.B.

CHUK, a new member of the helix-loop-helix and leucine zipper families of interacting proteins, contains a serine-threonine kinase catalytic domain.

Cell. Mol. Biol. Res.

41

537-549

1995

47118

Carninci P.,Kasukawa T.,Katayama S.,Gough J.,Frith M.C.,Maeda N.,Oyama R.,Ravasi T.,Lenhard B.,Wells C.,Kodzius R.,Shimokawa K.,Bajic V.B.,Brenner S.E.,Batalov S.,Forrest A.R.,Zavolan M.,Davis M.J.,Wilming L.G.,Aidinis V.,Allen J.E.,Ambesi-Impiombato A.,Apweiler R.,Aturaliya R.N.,Bailey T.L.,Bansal M.,Baxter L.,Beisel K.W.,Bersano T.,Bono H.,Chalk A.M.,Chiu K.P.,Choudhary V.,Christoffels A.,Clutterbuck D.R.,Crowe M.L.,Dalla E.,Dalrymple B.P.,de Bono B.,Della Gatta G.,di Bernardo D.,Down T.,Engstrom P.,Fagiolini M.,Faulkner G.,Fletcher C.F.,Fukushima T.,Furuno M.,Futaki S.,Gariboldi M.,Georgii-Hemming P.,Gingeras T.R.,Gojobori T.,Green R.E.,Gustincich S.,Harbers M.,Hayashi Y.,Hensch T.K.,Hirokawa N.,Hill D.,Huminiecki L.,Iacono M.,Ikeo K.,Iwama A.,Ishikawa T.,Jakt M.,Kanapin A.,Katoh M.,Kawasawa Y.,Kelso J.,Kitamura H.,Kitano H.,Kollias G.,Krishnan S.P.,Kruger A.,Kummerfeld S.K.,Kurochkin I.V.,Lareau L.F.,Lazarevic D.,Lipovich L.,Liu J.,Liuni S.,McWilliam S.,Madan Babu M.,Madera M.,Marchionni L.,Matsuda H.,Matsuzawa S.,Miki H.,Mignone F.,Miyake S.,Morris K.,Mottagui-Tabar S.,Mulder N.,Nakano N.,Nakauchi H.,Ng P.,Nilsson R.,Nishiguchi S.,Nishikawa S.,Nori F.,Ohara O.,Okazaki Y.,Orlando V.,Pang K.C.,Pavan W.J.,Pavesi G.,Pesole G.,Petrovsky N.,Piazza S.,Reed J.,Reid J.F.,Ring B.Z.,Ringwald M.,Rost B.,Ruan Y.,Salzberg S.L.,Sandelin A.,Schneider C.,Schoenbach C.,Sekiguchi K.,Semple C.A.,Seno S.,Sessa L.,Sheng Y.,Shibata Y.,Shimada H.,Shimada K.,Silva D.,Sinclair B.,Sperling S.,Stupka E.,Sugiura K.,Sultana R.,Takenaka Y.,Taki K.,Tammoja K.,Tan S.L.,Tang S.,Taylor M.S.,Tegner J.,Teichmann S.A.,Ueda H.R.,van Nimwegen E.,Verardo R.,Wei C.L.,Yagi K.,Yamanishi H.,Zabarovsky E.,Zhu S.,Zimmer A.,Hide W.,Bult C.,Grimmond S.M.,Teasdale R.D.,Liu E.T.,Brusic V.,Quackenbush J.,Wahlestedt C.,Mattick J.S.,Hume D.A.,Kai C.,Sasaki D.,Tomaru Y.,Fukuda S.,Kanamori-Katayama M.,Suzuki M.,Aoki J.,Arakawa T.,Iida J.,Imamura K.,Itoh M.,Kato T.,Kawaji H.,Kawagashira N.,Kawashima T.,Kojima M.,Kondo S.,Konno H.,Nakano K.,Ninomiya N.,Nishio T.,Okada M.,Plessy C.,Shibata K.,Shiraki T.,Suzuki S.,Tagami M.,Waki K.,Watahiki A.,Okamura-Oho Y.,Suzuki H.,Kawai J.,Hayashizaki Y.

The transcriptional landscape of the mammalian genome.

Science

309

1559-1563

2005

47119

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

Genome Res.

14

2121-2127

2004

47120

Takeda K.,Takeuchi O.,Tsujimura T.,Itami S.,Adachi O.,Kawai T.,Sanjo H.,Yoshikawa K.,Terada N.,Akira S.

Limb and skin abnormalities in mice lacking IKKalpha.

Science

284

313-316

1999

47121

McKenzie F.R.,Connelly M.A.,Balzarano D.,Mueller J.R.,Geleziunas R.,Marcu K.B.

Functional isoforms of IkappaB kinase alpha (IKKalpha) lacking leucine zipper and helix-loop-helix domains reveal that IKKalpha and IKKbeta have different activation requirements.

Mol. Cell. Biol.

20

2635-2649

2000

47122

Nakano H.,Shindo M.,Sakon S.,Nishinaka S.,Mihara M.,Yagita H.,Okumura K.

Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1.

Proc. Natl. Acad. Sci. U.S.A.

95

3537-3542

1998

47123

Delhase M.,Hayakawa M.,Chen Y.,Karin M.

Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation.

Science

284

309-313

1999

47124

Nemoto S.,DiDonato J.A.,Lin A.

Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinase.

Mol. Cell. Biol.

18

7336-7343

1998

47125

Jobin C.,Sartor R.B.

The I kappa B/NF-kappa B system: a key determinant of mucosal inflammation and protection.

Am. J. Physiol.

278

0-0

2000

47126

Soond S.M.,Terry J.L.,Colbert J.D.,Riches D.W.H.

TRUSS, a novel tumor necrosis factor receptor 1 scaffolding protein that mediates activation of the transcription factor NF-kappaB.

Mol. Cell. Biol.

23

8334-8344

2003

47127

Yamamoto Y.,Verma U.N.,Prajapati S.,Kwak Y.T.,Gaynor R.B.

Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression.

Nature

423

655-659

2003

47128

Kizaki T.,Izawa T.,Sakurai T.,Haga S.,Taniguchi N.,Tajiri H.,Watanabe K.,Day N.K.,Toba K.,Ohno H.

Beta2-adrenergic receptor regulates Toll-like receptor-4-induced nuclear factor-kappaB activation through beta-arrestin 2.

Immunology

124

348-356

2008

47129

Huttlin E.L.,Jedrychowski M.P.,Elias J.E.,Goswami T.,Rad R.,Beausoleil S.A.,Villen J.,Haas W.,Sowa M.E.,Gygi S.P.

A tissue-specific atlas of mouse protein phosphorylation and expression.

Cell

143

1174-1189

2010

47130

Teo H.,Ghosh S.,Luesch H.,Ghosh A.,Wong E.T.,Malik N.,Orth A.,de Jesus P.,Perry A.S.,Oliver J.D.,Tran N.L.,Speiser L.J.,Wong M.,Saez E.,Schultz P.,Chanda S.K.,Verma I.M.,Tergaonkar V.

Telomere-independent Rap1 is an IKK adaptor and regulates NF-kappaB-dependent gene expression.

Nat. Cell Biol.

12

758-767

2010

47131

Dondelinger Y.,Delanghe T.,Priem D.,Wynosky-Dolfi M.A.,Sorobetea D.,Rojas-Rivera D.,Giansanti P.,Roelandt R.,Gropengiesser J.,Ruckdeschel K.,Savvides S.N.,Heck A.J.R.,Vandenabeele P.,Brodsky I.E.,Bertrand M.J.M.

Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammation.

Nat. Commun.

10

1729-1729

2019