Sequence of HAOX1_HUMAN
EC Number:1.1.3.15
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
an (S)-2-hydroxy carboxylate + O2 = a 2-oxo carboxylate + H2O2
Other sequences found for EC No. 1.1.3.15
EC Number:1.2.3.5
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
glyoxylate + H2O + O2 = oxalate + H2O2
Other sequences found for EC No. 1.2.3.5
General information:
Sequence
0 MLPRLICIND YEQHAKSVLP KSIYDYYRSG ANDEETLADN IAAFSRWKLY PRMLRNVAET
60 DLSTSVLGQR VSMPICVGAT AMQRMAHVDG ELATVRACQS LGTGMMLSSW ATSSIEEVAE
120 AGPEALRWLQ LYIYKDREVT KKLVRQAEKM GYKAIFVTVD TPYLGNRLDD VRNRFKLPPQ
180 LRMKNFETST LSFSPEENFG DDSGLAAYVA KAIDPSISWE DIKWLRRLTS LPIVAKGILR
240 GDDAREAVKH GLNGILVSNH GARQLDGVPA TIDVLPEIVE AVEGKVEVFL DGGVRKGTDV
300 LKALALGAKA VFVGRPIVWG LAFQGEKGVQ DVLEILKEEF RLAMALSGCQ NVKVIDKTLV
360 RKNPLAVSKI
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
936310
Williams E.L.,Cregeen D.P.,Rumsby G.
Identification and expression of a cDNA for human glycolate oxidase.
Biochim. Biophys. Acta
1493
246-248
2000
936311
Jones J.M.,Morrell J.C.,Gould S.J.
Identification and characterization of HAOX1, HAOX2, and HAOX3, three human peroxisomal 2-hydroxy acid oxidases.
J. Biol. Chem.
275
12590-12597
2000
936314
Deloukas P.,Matthews L.H.,Ashurst J.L.,Burton J.,Gilbert J.G.R.,Jones M.,Stavrides G.,Almeida J.P.,Babbage A.K.,Bagguley C.L.,Bailey J.,Barlow K.F.,Bates K.N.,Beard L.M.,Beare D.M.,Beasley O.P.,Bird C.P.,Blakey S.E.,Bridgeman A.M.,Brown A.J.,Buck D.,Burrill W.D.,Butler A.P.,Carder C.,Carter N.P.,Chapman J.C.,Clamp M.,Clark G.,Clark L.N.,Clark S.Y.,Clee C.M.,Clegg S.,Cobley V.E.,Collier R.E.,Connor R.E.,Corby N.R.,Coulson A.,Coville G.J.,Deadman R.,Dhami P.D.,Dunn M.,Ellington A.G.,Frankland J.A.,Fraser A.,French L.,Garner P.,Grafham D.V.,Griffiths C.,Griffiths M.N.D.,Gwilliam R.,Hall R.E.,Hammond S.,Harley J.L.,Heath P.D.,Ho S.,Holden J.L.,Howden P.J.,Huckle E.,Hunt A.R.,Hunt S.E.,Jekosch K.,Johnson C.M.,Johnson D.,Kay M.P.,Kimberley A.M.,King A.,Knights A.,Laird G.K.,Lawlor S.,Lehvaeslaiho M.H.,Leversha M.A.,Lloyd C.,Lloyd D.M.,Lovell J.D.,Marsh V.L.,Martin S.L.,McConnachie L.J.,McLay K.,McMurray A.A.,Milne S.A.,Mistry D.,Moore M.J.F.,Mullikin J.C.,Nickerson T.,Oliver K.,Parker A.,Patel R.,Pearce T.A.V.,Peck A.I.,Phillimore B.J.C.T.,Prathalingam S.R.,Plumb R.W.,Ramsay H.,Rice C.M.,Ross M.T.,Scott C.E.,Sehra H.K.,Shownkeen R.,Sims S.,Skuce C.D.,Smith M.L.,Soderlund C.,Steward C.A.,Sulston J.E.,Swann R.M.,Sycamore N.,Taylor R.,Tee L.,Thomas D.W.,Thorpe A.,Tracey A.,Tromans A.C.,Vaudin M.,Wall M.,Wallis J.M.,Whitehead S.L.,Whittaker P.,Willey D.L.,Williams L.,Williams S.A.,Wilming L.,Wray P.W.,Hubbard T.,Durbin R.M.,Bentley D.R.,Beck S.,Rogers J.
The DNA sequence and comparative analysis of human chromosome 20.
Nature
414
865-871
2001
936315
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
936316
Vignaud C.,Pietrancosta N.,Williams E.L.,Rumsby G.,Lederer F.
Purification and characterization of recombinant human liver glycolate oxidase.
Arch. Biochem. Biophys.
465
410-416
2007
936317
Bian Y.,Song C.,Cheng K.,Dong M.,Wang F.,Huang J.,Sun D.,Wang L.,Ye M.,Zou H.
An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
J. Proteomics
96
253-262
2014
936318
Murray M.S.,Holmes R.P.,Lowther W.T.
Active site and loop 4 movements within human glycolate oxidase: implications for substrate specificity and drug design.
Biochemistry
47
2439-2449
2008
936319
Bourhis J.M.,Vignaud C.,Pietrancosta N.,Gueritte F.,Guenard D.,Lederer F.,Lindqvist Y.
Structure of human glycolate oxidase in complex with the inhibitor 4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazole.
Acta Crystallogr. F
65
1246-1253
2009
