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Sequence of PRPC_EMENI

EC Number:2.3.3.5

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
2-methylcitrate synthase
Q9TEM3
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
460
50580
Reaction
propanoyl-CoA + H2O + oxaloacetate = (2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate + CoA
Other sequences found for EC No. 2.3.3.5

EC Number:2.3.3.16

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
citrate synthase (unknown stereospecificity)
Q9TEM3
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
460
50580
Reaction
acetyl-CoA + H2O + oxaloacetate = citrate + CoA
Other sequences found for EC No. 2.3.3.16

General information:

Sequence
show sequence in fasta format
  0 MALPLRTARH ASRLAQTIGR RGYATAEPDL KSALKAVIPA KRELLAEVKK QGDEVIGEVK
 60 VSNVIGGMRG LKSMLWEGSV LDADEGIRFH GKTIKDCQKE LPKGPTGTEM LPEAMFWLLL
120 TGEVPSTSQV RAFSKQLAEE SHLPDHILDL AKSFPKHMHP MTQISIITAA LNTESKFAKL
180 YEKGINKADY WEPTFDDAIS LLAKIPRVAA LVFRPNEIDV VGRQKLDPAQ DWSYNFAELL
240 GKGGANNADF HDLLRLYLAL HGDHEGGNVS AHATHLVGSA LSDPFLSYSA GLLGLAGPLH
300 GLAAQEVLRW ILAMQEKIGT KFTDEDVRAY LWDTLKSGRV VPGYGHGVLR KPDPRFQALM
360 DFAATRKDVL ANPVFQLVKK NSEIAPGVLT EHGKTKNPHP NVDAASGVLF YHYGFQQPLY
420 YTVTFGVSRA LGPLVQLIWD RALGLPIERP KSINLLGLKK
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
844465
Brock M.,Fischer R.,Linder D.,Buckel W.
Methylcitrate synthase from Aspergillus nidulans: implications for propionate as an antifungal agent.
Mol. Microbiol.
35
961-973
2000
844466
Galagan J.E.,Calvo S.E.,Cuomo C.,Ma L.-J.,Wortman J.R.,Batzoglou S.,Lee S.-I.,Bastuerkmen M.,Spevak C.C.,Clutterbuck J.,Kapitonov V.,Jurka J.,Scazzocchio C.,Farman M.L.,Butler J.,Purcell S.,Harris S.,Braus G.H.,Draht O.,Busch S.,D'Enfert C.,Bouchier C.,Goldman G.H.,Bell-Pedersen D.,Griffiths-Jones S.,Doonan J.H.,Yu J.,Vienken K.,Pain A.,Freitag M.,Selker E.U.,Archer D.B.,Penalva M.A.,Oakley B.R.,Momany M.,Tanaka T.,Kumagai T.,Asai K.,Machida M.,Nierman W.C.,Denning D.W.,Caddick M.X.,Hynes M.,Paoletti M.,Fischer R.,Miller B.L.,Dyer P.S.,Sachs M.S.,Osmani S.A.,Birren B.W.
Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae.
Nature
438
1105-1115
2005
844467
Wortman J.R.,Gilsenan J.M.,Joardar V.,Deegan J.,Clutterbuck J.,Andersen M.R.,Archer D.,Bencina M.,Braus G.,Coutinho P.,von Dohren H.,Doonan J.,Driessen A.J.,Durek P.,Espeso E.,Fekete E.,Flipphi M.,Estrada C.G.,Geysens S.,Goldman G.,de Groot P.W.,Hansen K.,Harris S.D.,Heinekamp T.,Helmstaedt K.,Henrissat B.,Hofmann G.,Homan T.,Horio T.,Horiuchi H.,James S.,Jones M.,Karaffa L.,Karanyi Z.,Kato M.,Keller N.,Kelly D.E.,Kiel J.A.,Kim J.M.,van der Klei I.J.,Klis F.M.,Kovalchuk A.,Krasevec N.,Kubicek C.P.,Liu B.,Maccabe A.,Meyer V.,Mirabito P.,Miskei M.,Mos M.,Mullins J.,Nelson D.R.,Nielsen J.,Oakley B.R.,Osmani S.A.,Pakula T.,Paszewski A.,Paulsen I.,Pilsyk S.,Pocsi I.,Punt P.J.,Ram A.F.,Ren Q.,Robellet X.,Robson G.,Seiboth B.,van Solingen P.,Specht T.,Sun J.,Taheri-Talesh N.,Takeshita N.,Ussery D.,vanKuyk P.A.,Visser H.,van de Vondervoort P.J.,de Vries R.P.,Walton J.,Xiang X.,Xiong Y.,Zeng A.P.,Brandt B.W.,Cornell M.J.,van den Hondel C.A.,Visser J.,Oliver S.G.,Turner G.
The 2008 update of the Aspergillus nidulans genome annotation: a community effort.
Fungal Genet. Biol.
46
0-13
2009
844468
Brock M.,Buckel W.
On the mechanism of action of the antifungal agent propionate.
Eur. J. Biochem.
271
3227-3241
2004
844469
Zhang Y.Q.,Brock M.,Keller N.P.
Connection of propionyl-CoA metabolism to polyketide biosynthesis in Aspergillus nidulans.
Genetics
168
785-794
2004
844470
Zhang Y.Q.,Keller N.P.
Blockage of methylcitrate cycle inhibits polyketide production in Aspergillus nidulans.
Mol. Microbiol.
52
541-550
2004
844471
David H.,Hofmann G.,Oliveira A.P.,Jarmer H.,Nielsen J.
Metabolic network driven analysis of genome-wide transcription data from Aspergillus nidulans.
Genome Biol.
7
0-0
2006
844472
Fleck C.B.,Brock M.
Characterization of an acyl-CoA: carboxylate CoA-transferase from Aspergillus nidulans involved in propionyl-CoA detoxification.
Mol. Microbiol.
68
642-656
2008
844473
Murray S.L.,Hynes M.J.
Metabolic and developmental effects resulting from deletion of the citA gene encoding citrate synthase in Aspergillus nidulans.
Eukaryot. Cell
9
656-666
2010