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Sequence of ELMGT_STROV

EC Number:2.4.1.331

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
8-demethyltetracenomycin C L-rhamnosyltransferase
Q9F2F9
Streptomyces olivaceus
382
39465
Reaction
dTDP-beta-L-rhamnose + 8-demethyltetracenomycin C = dTDP + 8-demethyl-8-alpha-L-rhamnosyltetracenomycin C
Other sequences found for EC No. 2.4.1.331

General information:

Sequence
  0 MRVLAVATPA LGHLFPAVPL LWALRARGDE VLVVTGGDAL RVAEAGLPVV DALPGETLTT
 60 LFGAYQETDP AFFVALRRSP MTTLRDLAPV LAYLAGRLLE PARRAAERWR PDAILATHGQ
120 AAGAVVAAEH GIPLVEHGFG FVRSDGAQEA VRQLLAERLG PAGSEPPPER YFLDIAVPSM
180 TSAIEGMSLR AVPYNGGAVL PLSGASVGGR PPRPRVLVTA GTQLLHTHGA GALAWLPEVA
240 AGHEAEFLLA AGGADLRDLG RLPPHVRVLD WTPLATVLPT CSAVVHHGGS GTTLAALAAG
300 VPQLVSPALA DNHINARAVA DRGAGLETAV PDATTLTALL REPAFAKAAR EVADELRSLP
360 APADVAARLH TAFGLPTTQG DA
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
540043
Blanco G.,Patallo E.P.,Brana A.F.,Trefzer A.,Bechthold A.,Rohr J.,Mendez C.,Salas J.A.
Identification of a sugar flexible glycosyltransferase from Streptomyces olivaceus, the producer of the antitumor polyketide elloramycin.
Chem. Biol.
8
253-263
2001
540044
Patallo E.P.,Blanco G.,Fischer C.,Brana A.F.,Rohr J.,Mendez C.,Salas J.A.
Deoxysugar methylation during biosynthesis of the antitumor polyketide elloramycin by Streptomyces olivaceus. Characterization of three methyltransferase genes.
J. Biol. Chem.
276
18765-18774
2001
540045
Ramos A.,Lombo F.,Brana A.F.,Rohr J.,Mendez C.,Salas J.A.
Biosynthesis of elloramycin in Streptomyces olivaceus requires glycosylation by enzymes encoded outside the aglycon cluster.
Microbiology
154
781-788
2008
540046
Fischer C.,Rodriguez L.,Patallo E.P.,Lipata F.,Brana A.F.,Mendez C.,Salas J.A.,Rohr J.
Digitoxosyltetracenomycin C and glucosyltetracenomycin C, two novel elloramycin analogues obtained by exploring the sugar donor substrate specificity of glycosyltransferase ElmGT.
J. Nat. Prod.
65
1685-1689
2002
540047
Ramos A.,Olano C.,Brana A.F.,Mendez C.,Salas J.A.
Modulation of deoxysugar transfer by the elloramycin glycosyltransferase ElmGT through site-directed mutagenesis.
J. Bacteriol.
191
2871-2875
2009