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Sequence of Q9BMI9_SCHMA

EC Number:2.4.2.1

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
purine-nucleoside phosphorylase
Q9BMI9
Schistosoma mansoni
287
31162
Reaction
purine 2'-deoxyribonucleoside + phosphate = purine + 2-deoxy-alpha-D-ribose 1-phosphate
Other sequences found for EC No. 2.4.2.1

General information:

Sequence
show sequence in fasta format
  0 MHESVTANIE NVKKVAHHIQ KLTSIVPEIG IICGSGLGKL ADGVKDKITI PYTKIPNFPQ
 60 TSVVGHSGNL IFGTLSGRKV VVMQGRFHMY EGYSNDTVAL PIRVMKLLGV KILMVSNAAG
120 GLNRSLKLGD FVILKDHIYL PGLGLNNILV GPNQEAFGTR FPALSNAYDR DLRKLAVQVA
180 EENGFGNLVH QGVYVMNGGP CYETPAECTM LLNMGCDVVG MSTIPEVVIA RHCGIQVFAV
240 SLVTNISVLD VESDLKPNHE EVLATGAQRA ELMQSWFEKI IEKLPKD
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
152768960
Pereira H.D.,Franco G.R.,Cleasby A.,Garratt R.C.
Structures for the potential drug target purine nucleoside phosphorylase from Schistosoma mansoni causal agent of schistosomiasis.
J. Mol. Biol.
353
584-599
2005
152768962
Pereira H.M.,Rezende M.M.,Castilho M.S.,Oliva G.,Garratt R.C.
Adenosine binding to low-molecular-weight purine nucleoside phosphorylase: the structural basis for recognition based on its complex with the enzyme from Schistosoma mansoni.
Acta Crystallogr. D
66
73-79
2010
152768963
Pereira H.M.,Berdini V.,Ferri M.R.,Cleasby A.,Garratt R.C.
Crystal structure of Schistosoma purine nucleoside phosphorylase complexed with a novel monocyclic inhibitor.
Acta Trop.
114
97-102
2010
152768964
Castilho M.S.,Postigo M.P.,Pereira H.M.,Oliva G.,Andricopulo A.D.
Structural basis for selective inhibition of purine nucleoside phosphorylase from Schistosoma mansoni: kinetic and structural studies.
Bioorg. Med. Chem.
18
1421-1427
2010
152768965
D'Muniz Pereira H.,Oliva G.,Garratt R.C.
Purine nucleoside phosphorylase from Schistosoma mansoni in complex with ribose-1-phosphate.
J. Synchrotron Radiat.
18
62-65
2011