Sequence of PARK7_HUMAN
EC Number:3.1.2
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
Other sequences found for EC No. 3.1.2
EC Number:3.5.1
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
Other sequences found for EC No. 3.5.1
EC Number:3.4
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
Other sequences found for EC No. 3.4
EC Number:3.5.1.124
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
an N6-(1-hydroxy-2-oxopropyl)-[protein]-L-lysine + H2O = a [protein]-L-lysine + lactate
Other sequences found for EC No. 3.5.1.124
EC Number:4.2.1.130
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
(R)-lactate = 2-oxopropanal + H2O
Other sequences found for EC No. 4.2.1.130
General information:
Sequence
0 MASKRALVIL AKGAEEMETV IPVDVMRRAG IKVTVAGLAG KDPVQCSRDV VICPDASLED
60 AKKEGPYDVV VLPGGNLGAQ NLSESAAVKE ILKEQENRKG LIAAICAGPT ALLAHEIGFG
120 SKVTTHPLAK DKMMNGGHYT YSENRVEKDG LILTSRGPGT SFEFALAIVE ALNGKEVAAQ
180 VKAPLVLKD
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1096921
Nagakubo D.,Taita T.,Kitaura H.,Ikeda M.,Tamai K.,Iguchi-Ariga S.M.M.,Ariga H.
DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras.
Biochem. Biophys. Res. Commun.
231
509-513
1997
1096924
Ota T.,Suzuki Y.,Nishikawa T.,Otsuki T.,Sugiyama T.,Irie R.,Wakamatsu A.,Hayashi K.,Sato H.,Nagai K.,Kimura K.,Makita H.,Sekine M.,Obayashi M.,Nishi T.,Shibahara T.,Tanaka T.,Ishii S.,Yamamoto J.,Saito K.,Kawai Y.,Isono Y.,Nakamura Y.,Nagahari K.,Murakami K.,Yasuda T.,Iwayanagi T.,Wagatsuma M.,Shiratori A.,Sudo H.,Hosoiri T.,Kaku Y.,Kodaira H.,Kondo H.,Sugawara M.,Takahashi M.,Kanda K.,Yokoi T.,Furuya T.,Kikkawa E.,Omura Y.,Abe K.,Kamihara K.,Katsuta N.,Sato K.,Tanikawa M.,Yamazaki M.,Ninomiya K.,Ishibashi T.,Yamashita H.,Murakawa K.,Fujimori K.,Tanai H.,Kimata M.,Watanabe M.,Hiraoka S.,Chiba Y.,Ishida S.,Ono Y.,Takiguchi S.,Watanabe S.,Yosida M.,Hotuta T.,Kusano J.,Kanehori K.,Takahashi-Fujii A.,Hara H.,Tanase T.-O.,Nomura Y.,Togiya S.,Komai F.,Hara R.,Takeuchi K.,Arita M.,Imose N.,Musashino K.,Yuuki H.,Oshima A.,Sasaki N.,Aotsuka S.,Yoshikawa Y.,Matsunawa H.,Ichihara T.,Shiohata N.,Sano S.,Moriya S.,Momiyama H.,Satoh N.,Takami S.,Terashima Y.,Suzuki O.,Nakagawa S.,Senoh A.,Mizoguchi H.,Goto Y.,Shimizu F.,Wakebe H.,Hishigaki H.,Watanabe T.,Sugiyama A.,Takemoto M.,Kawakami B.,Yamazaki M.,Watanabe K.,Kumagai A.,Itakura S.,Fukuzumi Y.,Fujimori Y.,Komiyama M.,Tashiro H.,Tanigami A.,Fujiwara T.,Ono T.,Yamada K.,Fujii Y.,Ozaki K.,Hirao M.,Ohmori Y.,Kawabata A.,Hikiji T.,Kobatake N.,Inagaki H.,Ikema Y.,Okamoto S.,Okitani R.,Kawakami T.,Noguchi S.,Itoh T.,Shigeta K.,Senba T.,Matsumura K.,Nakajima Y.,Mizuno T.,Morinaga M.,Sasaki M.,Togashi T.,Oyama M.,Hata H.,Watanabe M.,Komatsu T.,Mizushima-Sugano J.,Satoh T.,Shirai Y.,Takahashi Y.,Nakagawa K.,Okumura K.,Nagase T.,Nomura N.,Kikuchi H.,Masuho Y.,Yamashita R.,Nakai K.,Yada T.,Nakamura Y.,Ohara O.,Isogai T.,Sugano S.
Complete sequencing and characterization of 21,243 full-length human cDNAs.
Nat. Genet.
36
40-45
2004
1096925
Gregory S.G.,Barlow K.F.,McLay K.E.,Kaul R.,Swarbreck D.,Dunham A.,Scott C.E.,Howe K.L.,Woodfine K.,Spencer C.C.A.,Jones M.C.,Gillson C.,Searle S.,Zhou Y.,Kokocinski F.,McDonald L.,Evans R.,Phillips K.,Atkinson A.,Cooper R.,Jones C.,Hall R.E.,Andrews T.D.,Lloyd C.,Ainscough R.,Almeida J.P.,Ambrose K.D.,Anderson F.,Andrew R.W.,Ashwell R.I.S.,Aubin K.,Babbage A.K.,Bagguley C.L.,Bailey J.,Beasley H.,Bethel G.,Bird C.P.,Bray-Allen S.,Brown J.Y.,Brown A.J.,Buckley D.,Burton J.,Bye J.,Carder C.,Chapman J.C.,Clark S.Y.,Clarke G.,Clee C.,Cobley V.,Collier R.E.,Corby N.,Coville G.J.,Davies J.,Deadman R.,Dunn M.,Earthrowl M.,Ellington A.G.,Errington H.,Frankish A.,Frankland J.,French L.,Garner P.,Garnett J.,Gay L.,Ghori M.R.J.,Gibson R.,Gilby L.M.,Gillett W.,Glithero R.J.,Grafham D.V.,Griffiths C.,Griffiths-Jones S.,Grocock R.,Hammond S.,Harrison E.S.I.,Hart E.,Haugen E.,Heath P.D.,Holmes S.,Holt K.,Howden P.J.,Hunt A.R.,Hunt S.E.,Hunter G.,Isherwood J.,James R.,Johnson C.,Johnson D.,Joy A.,Kay M.,Kershaw J.K.,Kibukawa M.,Kimberley A.M.,King A.,Knights A.J.,Lad H.,Laird G.,Lawlor S.,Leongamornlert D.A.,Lloyd D.M.,Loveland J.,Lovell J.,Lush M.J.,Lyne R.,Martin S.,Mashreghi-Mohammadi M.,Matthews L.,Matthews N.S.W.,McLaren S.,Milne S.,Mistry S.,Moore M.J.F.,Nickerson T.,O'Dell C.N.,Oliver K.,Palmeiri A.,Palmer S.A.,Parker A.,Patel D.,Pearce A.V.,Peck A.I.,Pelan S.,Phelps K.,Phillimore B.J.,Plumb R.,Rajan J.,Raymond C.,Rouse G.,Saenphimmachak C.,Sehra H.K.,Sheridan E.,Shownkeen R.,Sims S.,Skuce C.D.,Smith M.,Steward C.,Subramanian S.,Sycamore N.,Tracey A.,Tromans A.,Van Helmond Z.,Wall M.,Wallis J.M.,White S.,Whitehead S.L.,Wilkinson J.E.,Willey D.L.,Williams H.,Wilming L.,Wray P.W.,Wu Z.,Coulson A.,Vaudin M.,Sulston J.E.,Durbin R.M.,Hubbard T.,Wooster R.,Dunham I.,Carter N.P.,McVean G.,Ross M.T.,Harrow J.,Olson M.V.,Beck S.,Rogers J.,Bentley D.R.
The DNA sequence and biological annotation of human chromosome 1.
Nature
441
315-321
2006
1096927
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
1096928
Taira T.,Takahashi K.,Kitagawa R.,Iguchi-Ariga S.M.M.,Ariga H.
Molecular cloning of human and mouse DJ-1 genes and identification of Sp1-dependent activation of the human DJ-1 promoter.
Gene
263
285-292
2001
1096931
Takahashi K.,Taira T.,Niki T.,Seino C.,Iguchi-Ariga S.M.M.,Ariga H.
DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor.
J. Biol. Chem.
276
37556-37563
2001
1096932
Miller D.W.,Ahmad R.,Hague S.,Baptista M.J.,Canet-Aviles R.,McLendon C.,Carter D.M.,Zhu P.-P.,Stadler J.,Chandran J.,Klinefelter G.R.,Blackstone C.,Cookson M.R.
L166P mutant DJ-1, causative for recessive Parkinson's disease, is degraded through the ubiquitin-proteasome system.
J. Biol. Chem.
278
36588-36595
2003
1096933
Moore D.J.,Zhang L.,Dawson T.M.,Dawson V.L.
A missense mutation (L166P) in DJ-1, linked to familial Parkinson's disease, confers reduced protein stability and impairs homo-oligomerization.
J. Neurochem.
87
1558-1567
2003
1096934
Niki T.,Takahashi-Niki K.,Taira T.,Iguchi-Ariga S.M.M.,Ariga H.
DJBP: a novel DJ-1-binding protein, negatively regulates the androgen receptor by recruiting histone deacetylase complex, and DJ-1 antagonizes this inhibition by abrogation of this complex.
Mol. Cancer Res.
1
247-261
2003
1096935
Yoshida K.,Sato Y.,Yoshiike M.,Nozawa S.,Ariga H.,Iwamoto T.
Immunocytochemical localization of DJ-1 in human male reproductive tissue.
Mol. Reprod. Dev.
66
391-397
2003
1096936
Rizzu P.,Hinkle D.A.,Zhukareva V.,Bonifati V.,Severijnen L.-A.,Martinez D.,Ravid R.,Kamphorst W.,Eberwine J.H.,Lee V.M.-Y.,Trojanowski J.Q.,Heutink P.
DJ-1 colocalizes with tau inclusions: a link between parkinsonism and dementia.
Ann. Neurol.
55
113-118
2004
1096937
Bandopadhyay R.,Kingsbury A.E.,Cookson M.R.,Reid A.R.,Evans I.M.,Hope A.D.,Pittman A.M.,Lashley T.,Canet-Aviles R.,Miller D.W.,McLendon C.,Strand C.,Leonard A.J.,Abou-Sleiman P.M.,Healy D.G.,Ariga H.,Wood N.W.,de Silva R.,Revesz T.,Hardy J.A.,Lees A.J.
The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease.
Brain
127
420-430
2004
1096938
Taira T.,Saito Y.,Niki T.,Iguchi-Ariga S.M.,Takahashi K.,Ariga H.
DJ-1 has a role in antioxidative stress to prevent cell death.
EMBO Rep.
5
213-218
2004
1096939
Shendelman S.,Jonason A.,Martinat C.,Leete T.,Abeliovich A.
DJ-1 is a redox-dependent molecular chaperone that inhibits alpha-synuclein aggregate formation.
PLoS Biol.
2
1-10
2004
1096940
Rush J.,Moritz A.,Lee K.A.,Guo A.,Goss V.L.,Spek E.J.,Zhang H.,Zha X.-M.,Polakiewicz R.D.,Comb M.J.
Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.
Nat. Biotechnol.
23
94-101
2005
1096941
Shinbo Y.,Niki T.,Taira T.,Ooe H.,Takahashi-Niki K.,Maita C.,Seino C.,Iguchi-Ariga S.M.M.,Ariga H.
Proper SUMO-1 conjugation is essential to DJ-1 to exert its full activities.
Cell Death Differ.
13
96-108
2006
1096942
Sekito A.,Koide-Yoshida S.,Niki T.,Taira T.,Iguchi-Ariga S.M.M.,Ariga H.
DJ-1 interacts with HIPK1 and affects H2O2-induced cell death.
Free Radic. Res.
40
155-165
2006
1096943
Clements C.M.,McNally R.S.,Conti B.J.,Mak T.W.,Ting J.P.
DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2.
Proc. Natl. Acad. Sci. U.S.A.
103
15091-15096
2006
1096944
van der Brug M.P.,Blackinton J.,Chandran J.,Hao L.Y.,Lal A.,Mazan-Mamczarz K.,Martindale J.,Xie C.,Ahmad R.,Thomas K.J.,Beilina A.,Gibbs J.R.,Ding J.,Myers A.J.,Zhan M.,Cai H.,Bonini N.M.,Gorospe M.,Cookson M.R.
RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways.
Proc. Natl. Acad. Sci. U.S.A.
105
10244-10249
2008
1096945
Xiong H.,Wang D.,Chen L.,Choo Y.S.,Ma H.,Tang C.,Xia K.,Jiang W.,Ronai Z.,Zhuang X.,Zhang Z.
Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation.
J. Clin. Invest.
119
650-660
2009
1096946
Junn E.,Jang W.H.,Zhao X.,Jeong B.S.,Mouradian M.M.
Mitochondrial localization of DJ-1 leads to enhanced neuroprotection.
J. Neurosci. Res.
87
123-129
2009
1096947
Chen J.,Li L.,Chin L.S.
Parkinson disease protein DJ-1 converts from a zymogen to a protease by carboxyl-terminal cleavage.
Hum. Mol. Genet.
19
2395-2408
2010
1096948
Burkard T.R.,Planyavsky M.,Kaupe I.,Breitwieser F.P.,Buerckstuemmer T.,Bennett K.L.,Superti-Furga G.,Colinge J.
Initial characterization of the human central proteome.
BMC Syst. Biol.
5
17-17
2011
1096949
McNally R.S.,Davis B.K.,Clements C.M.,Accavitti-Loper M.A.,Mak T.W.,Ting J.P.
DJ-1 enhances cell survival through the binding of cezanne, a negative regulator of NF-{kappa}B.
J. Biol. Chem.
286
4098-4106
2011
1096950
Lee J.Y.,Song J.,Kwon K.,Jang S.,Kim C.,Baek K.,Kim J.,Park C.
Human DJ-1 and its homologs are novel glyoxalases.
Hum. Mol. Genet.
21
3215-3225
2012
1096951
Jain D.,Jain R.,Eberhard D.,Eglinger J.,Bugliani M.,Piemonti L.,Marchetti P.,Lammert E.
Age- and diet-dependent requirement of DJ-1 for glucose homeostasis in mice with implications for human type 2 diabetes.
J. Mol. Cell Biol.
4
221-230
2012
1096952
Kim K.S.,Kim J.S.,Park J.Y.,Suh Y.H.,Jou I.,Joe E.H.,Park S.M.
DJ-1 associates with lipid rafts by palmitoylation and regulates lipid rafts-dependent endocytosis in astrocytes.
Hum. Mol. Genet.
22
4805-4817
2013
1096953
Bjorkblom B.,Adilbayeva A.,Maple-Grodem J.,Piston D.,Okvist M.,Xu X.M.,Brede C.,Larsen J.P.,Moller S.G.
Parkinson disease protein DJ-1 binds metals and protects against metal-induced cytotoxicity.
J. Biol. Chem.
288
22809-22820
2013
1096954
Bian Y.,Song C.,Cheng K.,Dong M.,Wang F.,Huang J.,Sun D.,Wang L.,Ye M.,Zou H.
An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
J. Proteomics
96
253-262
2014
1096955
Richarme G.,Mihoub M.,Dairou J.,Bui L.C.,Leger T.,Lamouri A.
Parkinsonism-associated protein DJ-1/Park7 is a major protein deglycase that repairs methylglyoxal- and glyoxal-glycated cysteine, arginine and lysine residues.
J. Biol. Chem.
290
1885-1897
2015
1096956
Vaca Jacome A.S.,Rabilloud T.,Schaeffer-Reiss C.,Rompais M.,Ayoub D.,Lane L.,Bairoch A.,Van Dorsselaer A.,Carapito C.
N-terminome analysis of the human mitochondrial proteome.
Proteomics
15
2519-2524
2015
1096957
Pfaff D.H.,Fleming T.,Nawroth P.,Teleman A.A.
Evidence against a role for the Parkinsonism-associated protein DJ-1 in methylglyoxal detoxification.
J. Biol. Chem.
292
685-690
2017
1096958
Richarme G.,Dairou J.
Parkinsonism-associated protein DJ-1 is a bona fide deglycase.
Biochem. Biophys. Res. Commun.
483
387-391
2017
1096959
Advedissian T.,Deshayes F.,Poirier F.,Viguier M.,Richarme G.
The Parkinsonism-associated protein DJ-1/Park7 prevents glycation damage in human keratinocyte.
Biochem. Biophys. Res. Commun.
473
87-91
2016
1096960
Richarme G.,Liu C.,Mihoub M.,Abdallah J.,Leger T.,Joly N.,Liebart J.C.,Jurkunas U.V.,Nadal M.,Bouloc P.,Dairou J.,Lamouri A.
Guanine glycation repair by DJ-1/Park7 and its bacterial homologs.
Science
357
208-211
2017
1096961
Matsuda N.,Kimura M.,Queliconi B.B.,Kojima W.,Mishima M.,Takagi K.,Koyano F.,Yamano K.,Mizushima T.,Ito Y.,Tanaka K.
Parkinson's disease-related DJ-1 functions in thiol quality control against aldehyde attack in vitro.
Sci. Rep.
7
12816-12816
2017
1096962
Galligan J.J.,Wepy J.A.,Streeter M.D.,Kingsley P.J.,Mitchener M.M.,Wauchope O.R.,Beavers W.N.,Rose K.L.,Wang T.,Spiegel D.A.,Marnett L.J.
Methylglyoxal-derived posttranslational arginine modifications are abundant histone marks.
Proc. Natl. Acad. Sci. U.S.A.
115
9228-9233
2018
1096963
Moutaoufik M.T.,Malty R.,Amin S.,Zhang Q.,Phanse S.,Gagarinova A.,Zilocchi M.,Hoell L.,Minic Z.,Gagarinova M.,Aoki H.,Stockwell J.,Jessulat M.,Goebels F.,Broderick K.,Scott N.E.,Vlasblom J.,Musso G.,Prasad B.,Lamantea E.,Garavaglia B.,Rajput A.,Murayama K.,Okazaki Y.,Foster L.J.,Bader G.D.,Cayabyab F.S.,Babu M.
Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.
IScience
19
1114-1132
2019
1096964
Andreeva A.,Bekkhozhin Z.,Omertassova N.,Baizhumanov T.,Yeltay G.,Akhmetali M.,Toibazar D.,Utepbergenov D.
The apparent deglycase activity of DJ-1 results from the conversion of free methylglyoxal present in fast equilibrium with hemithioacetals and hemiaminals.
J. Biol. Chem.
294
18863-18872
2019
1096965
Zheng Q.,Omans N.D.,Leicher R.,Osunsade A.,Agustinus A.S.,Finkin-Groner E.,D'Ambrosio H.,Liu B.,Chandarlapaty S.,Liu S.,David Y.
Reversible histone glycation is associated with disease-related changes in chromatin architecture.
Nat. Commun.
10
1289-1289
2019
1096966
Huai Q.,Sun Y.,Wang H.,Chin L.-S.,Li L.,Robinson H.,Ke H.
Crystal structure of DJ-1/RS and implication on familial Parkinson's disease.
FEBS Lett.
549
171-175
2003
1096967
Tao X.,Tong L.
Crystal structure of human DJ-1, a protein associated with early onset Parkinson's disease.
J. Biol. Chem.
278
31372-31379
2003
1096968
Honbou K.,Suzuki N.N.,Horiuchi M.,Niki T.,Taira T.,Ariga H.,Inagaki F.
The crystal structure of DJ-1, a protein related to male fertility and Parkinson's disease.
J. Biol. Chem.
278
31380-31384
2003
1096969
Lee S.-J.,Kim S.J.,Kim I.-K.,Ko J.,Jeong C.-S.,Kim G.-H.,Park C.,Kang S.-O.,Suh P.-G.,Lee H.-S.,Cha S.-S.
Crystal structures of human DJ-1 and Escherichia coli Hsp31, which share an evolutionarily conserved domain.
J. Biol. Chem.
278
44552-44559
2003
1096970
Wilson M.A.,Collins J.L.,Hod Y.,Ringe D.,Petsko G.A.
The 1.1-A resolution crystal structure of DJ-1, the protein mutated in autosomal recessive early onset Parkinson's disease.
Proc. Natl. Acad. Sci. U.S.A.
100
9256-9261
2003
1096971
Canet-Aviles R.M.,Wilson M.A.,Miller D.W.,Ahmad R.,McLendon C.,Bandyopadhyay S.,Baptista M.J.,Ringe D.,Petsko G.A.,Cookson M.R.
The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization.
Proc. Natl. Acad. Sci. U.S.A.
101
9103-9108
2004
1096972
Abou-Sleiman P.M.,Healy D.G.,Quinn N.,Lees A.J.,Wood N.W.
The role of pathogenic DJ-1 mutations in Parkinson's disease.
Ann. Neurol.
54
283-286
2003
1096973
Bonifati V.,Rizzu P.,van Baren M.J.,Schaap O.,Breedveld G.J.,Krieger E.,Dekker M.C.J.,Squitieri F.,Ibanez P.,Joosse M.,van Dongen J.W.,Vanacore N.,van Swieten J.C.,Brice A.,Meco G.,van Duijn C.M.,Oostra B.A.,Heutink P.
Mutations in the DJ-1 gene associated with autosomal recessive early-onset Parkinsonism.
Science
299
256-259
2003
1096974
Hedrich K.,Schaefer N.,Hering R.,Hagenah J.,Lanthaler A.J.,Schwinger E.,Kramer P.L.,Ozelius L.J.,Bressman S.B.,Abbruzzese G.,Martinelli P.,Kostic V.,Pramstaller P.P.,Vieregge P.,Riess O.,Klein C.
The R98Q variation in DJ-1 represents a rare polymorphism.
Ann. Neurol.
55
145-146
2004
1096975
Hering R.,Strauss K.M.,Tao X.,Bauer A.,Woitalla D.,Mietz E.M.,Petrovic S.,Bauer P.,Schaible W.,Mueller T.,Schoels L.,Klein C.,Berg D.,Meyer P.T.,Schulz J.B.,Wollnik B.,Tong L.,Krueger R.,Riess O.
Novel homozygous p.E64D mutation in DJ1 in early onset Parkinson disease (PARK7).
Hum. Mutat.
24
321-329
2004
1096976
Goerner K.,Holtorf E.,Odoy S.,Nuscher B.,Yamamoto A.,Regula J.T.,Beyer K.,Haass C.,Kahle P.J.
Differential effects of Parkinson's disease-associated mutations on stability and folding of DJ-1.
J. Biol. Chem.
279
6943-6951
2004
1096977
Clark L.N.,Afridi S.,Mejia-Santana H.,Harris J.,Louis E.D.,Cote L.J.,Andrews H.,Singleton A.,Wavrant De-Vrieze F.,Hardy J.,Mayeux R.,Fahn S.,Waters C.,Ford B.,Frucht S.,Ottman R.,Marder K.
Analysis of an early-onset Parkinson's disease cohort for DJ-1 mutations.
Mov. Disord.
19
796-800
2004
1096978
Hedrich K.,Djarmati A.,Schafer N.,Hering R.,Wellenbrock C.,Weiss P.H.,Hilker R.,Vieregge P.,Ozelius L.J.,Heutink P.,Bonifati V.,Schwinger E.,Lang A.E.,Noth J.,Bressman S.B.,Pramstaller P.P.,Riess O.,Klein C.
DJ-1 (PARK7) mutations are less frequent than Parkin (PARK2) mutations in early-onset Parkinson disease.
Neurology
62
389-394
2004
1096979
Annesi G.,Savettieri G.,Pugliese P.,D'Amelio M.,Tarantino P.,Ragonese P.,La Bella V.,Piccoli T.,Civitelli D.,Annesi F.,Fierro B.,Piccoli F.,Arabia G.,Caracciolo M.,Ciro Candiano I.C.,Quattrone A.
DJ-1 mutations and parkinsonism-dementia-amyotrophic lateral sclerosis complex.
Ann. Neurol.
58
803-807
2005
1096980
Tang B.,Xiong H.,Sun P.,Zhang Y.,Wang D.,Hu Z.,Zhu Z.,Ma H.,Pan Q.,Xia J.-H.,Xia K.,Zhang Z.
Association of PINK1 and DJ-1 confers digenic inheritance of early-onset Parkinson's disease.
Hum. Mol. Genet.
15
1816-1825
2006
1096981
Olzmann J.A.,Li L.,Chudaev M.V.,Chen J.,Perez F.A.,Palmiter R.D.,Chin L.S.
Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6.
J. Cell Biol.
178
1025-1038
2007
1096982
Guo J.F.,Xiao B.,Liao B.,Zhang X.W.,Nie L.L.,Zhang Y.H.,Shen L.,Jiang H.,Xia K.,Pan Q.,Yan X.X.,Tang B.S.
Mutation analysis of Parkin, PINK1, DJ-1 and ATP13A2 genes in Chinese patients with autosomal recessive early-onset Parkinsonism.
Mov. Disord.
23
2074-2079
2008
1096983
Krebiehl G.,Ruckerbauer S.,Burbulla L.F.,Kieper N.,Maurer B.,Waak J.,Wolburg H.,Gizatullina Z.,Gellerich F.N.,Woitalla D.,Riess O.,Kahle P.J.,Proikas-Cezanne T.,Kruger R.
Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1.
PLoS ONE
5
0-0
2010
1096984
Hanagasi H.A.,Giri A.,Kartal E.,Guven G.,Bilgic B.,Hauser A.K.,Emre M.,Heutink P.,Basak N.,Gasser T.,Simon-Sanchez J.,Lohmann E.
A novel homozygous DJ1 mutation causes parkinsonism and ALS in a Turkish family.
Parkinsonism Relat. Disord.
29
117-120
2016
1096985
Stephenson S.E.,Djaldetti R.,Rafehi H.,Wilson G.R.,Gillies G.,Bahlo M.,Lockhart P.J.
Familial early onset Parkinson's disease caused by a homozygous frameshift variant in PARK7: Clinical features and literature update.
Parkinsonism Relat. Disord.
64
308-311
2019
