Sequence of Q8U0A9_PYRFU
EC Number:2.5.1.54
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
3-deoxy-7-phosphoheptulonate synthase
Q8U0A9
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
262
29225
Reaction
phosphoenolpyruvate + D-erythrose 4-phosphate + H2O = 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate + phosphate
Other sequences found for EC No. 2.5.1.54
EC Number:2.5.1.54
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
phosphoenolpyruvate + D-erythrose 4-phosphate + H2O = 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate + phosphate
Other sequences found for EC No. 2.5.1.54
General information:
Sequence
0 MKYSKEYKEK TVVKINDVKF GEGFTIIAGP CSIESRDQIM KVAEFLAEVG IKVLRGGAFK
60 PRTSPYSFQG YGEKALRWMR EAADEYGLVT VTEVMDTRHV ELVAKYSDIL QIGARNSQNF
120 ELLKEVGKVE NPVLLKRGMG NTIQELLYSA EYIMAQGNEN VILCERGIRT FETATRFTLD
180 ISAVPVVKEL SHLPIIVDPS HPAGRRSLVI PLAKAAYAIG ADGIMVEVHP EPEKALSDSQ
240 QQLTFDDFLQ LLKELEALGW KG
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
81265293
Maeder D.L.,Weiss R.B.,Dunn D.M.,Cherry J.L.,Gonzalez J.M.,DiRuggiero J.,Robb F.T.
Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P. horikoshii inferred from complete genomic sequences.
Genetics
152
1299-1305
1999
81265294
Schofield L.R.,Anderson B.F.,Patchett M.L.,Norris G.E.,Jameson G.B.,Parker E.J.
Substrate ambiguity and crystal structure of Pyrococcus furiosus 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase: an ancestral 3-deoxyald-2-ulosonate-phosphate synthase?
Biochemistry
44
11950-11962
2005
81265295
Cross P.J.,Allison T.M.,Dobson R.C.,Jameson G.B.,Parker E.J.
Engineering allosteric control to an unregulated enzyme by transfer of a regulatory domain.
Proc. Natl. Acad. Sci. U.S.A.
110
2111-2116
2013
81265296
Nazmi A.R.,Schofield L.R.,Dobson R.C.,Jameson G.B.,Parker E.J.
Destabilization of the homotetrameric assembly of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from the hyperthermophile Pyrococcus furiosus enhances enzymatic activity.
J. Mol. Biol.
426
656-673
2014
