Sequence of PNPH_PLAF7
EC Number:2.4.2.1
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
purine 2'-deoxyribonucleoside + phosphate = purine + 2-deoxy-alpha-D-ribose 1-phosphate
Other sequences found for EC No. 2.4.2.1
EC Number:2.4.2.3
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
uridine + phosphate = uracil + alpha-D-ribose 1-phosphate
Other sequences found for EC No. 2.4.2.3
EC Number:2.4.2.44
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
S-methyl-5'-thioinosine phosphorylase
Q8I3X4
Plasmodium falciparum (isolate 3D7)
245
26858
Reaction
S-methyl-5'-thioinosine + phosphate = hypoxanthine + S-methyl-5-thio-alpha-D-ribose 1-phosphate
Other sequences found for EC No. 2.4.2.44
General information:
Sequence
0 MDNLLRHLKI SKEQITPVVL VVGDPGRVDK IKVVCDSYVD LAYNREYKSV ECHYKGQKFL
60 CVSHGVGSAG CAVCFEELCQ NGAKVIIRAG SCGSLQPDLI KRGDICICNA AVREDRVSHL
120 LIHGDFPAVG DFDVYDTLNK CAQELNVPVF NGISVSSDMY YPNKIIPSRL EDYSKANAAV
180 VEMELATLMV IGTLRKVKTG GILIVDGCPF KWDEGDFDNN LVPHQLENMI KIALGACAKL
240 ATKYA
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1231192
Gardner M.J.,Hall N.,Fung E.,White O.,Berriman M.,Hyman R.W.,Carlton J.M.,Pain A.,Nelson K.E.,Bowman S.,Paulsen I.T.,James K.D.,Eisen J.A.,Rutherford K.M.,Salzberg S.L.,Craig A.,Kyes S.,Chan M.-S.,Nene V.,Shallom S.J.,Suh B.,Peterson J.,Angiuoli S.,Pertea M.,Allen J.,Selengut J.,Haft D.,Mather M.W.,Vaidya A.B.,Martin D.M.A.,Fairlamb A.H.,Fraunholz M.J.,Roos D.S.,Ralph S.A.,McFadden G.I.,Cummings L.M.,Subramanian G.M.,Mungall C.,Venter J.C.,Carucci D.J.,Hoffman S.L.,Newbold C.,Davis R.W.,Fraser C.M.,Barrell B.G.
Genome sequence of the human malaria parasite Plasmodium falciparum.
Nature
419
498-511
2002
1231193
Hall N.,Pain A.,Berriman M.,Churcher C.M.,Harris B.,Harris D.,Mungall K.L.,Bowman S.,Atkin R.,Baker S.,Barron A.,Brooks K.,Buckee C.O.,Burrows C.,Cherevach I.,Chillingworth C.,Chillingworth T.,Christodoulou Z.,Clark L.,Clark R.,Corton C.,Cronin A.,Davies R.M.,Davis P.,Dear P.,Dearden F.,Doggett J.,Feltwell T.,Goble A.,Goodhead I.,Gwilliam R.,Hamlin N.,Hance Z.,Harper D.,Hauser H.,Hornsby T.,Holroyd S.,Horrocks P.,Humphray S.,Jagels K.,James K.D.,Johnson D.,Kerhornou A.,Knights A.,Konfortov B.,Kyes S.,Larke N.,Lawson D.,Lennard N.,Line A.,Maddison M.,Mclean J.,Mooney P.,Moule S.,Murphy L.,Oliver K.,Ormond D.,Price C.,Quail M.A.,Rabbinowitsch E.,Rajandream M.A.,Rutter S.,Rutherford K.M.,Sanders M.,Simmonds M.,Seeger K.,Sharp S.,Smith R.,Squares R.,Squares S.,Stevens K.,Taylor K.,Tivey A.,Unwin L.,Whitehead S.,Woodward J.R.,Sulston J.E.,Craig A.,Newbold C.,Barrell B.G.
Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.
Nature
419
527-531
2002
1231194
Madrid D.C.,Ting L.M.,Waller K.L.,Schramm V.L.,Kim K.
Plasmodium falciparum purine nucleoside phosphorylase is critical for viability of malaria parasites.
J. Biol. Chem.
283
35899-35907
2008
1231195
Shi W.,Ting L.M.,Kicska G.A.,Lewandowicz A.,Tyler P.C.,Evans G.B.,Furneaux R.H.,Kim K.,Almo S.C.,Schramm V.L.
Plasmodium falciparum purine nucleoside phosphorylase: crystal structures, immucillin inhibitors, and dual catalytic function.
J. Biol. Chem.
279
18103-18106
2004
1231196
Schnick C.,Robien M.A.,Brzozowski A.M.,Dodson E.J.,Murshudov G.N.,Anderson L.,Luft J.R.,Mehlin C.,Hol W.G.,Brannigan J.A.,Wilkinson A.J.
Structures of Plasmodium falciparum purine nucleoside phosphorylase complexed with sulfate and its natural substrate inosine.
Acta Crystallogr. D
61
1245-1254
2005
1231197
Chaikuad A.,Brady R.L.
Conservation of structure and activity in Plasmodium purine nucleoside phosphorylases.
BMC Struct. Biol.
9
42-42
2009
1231199
Donaldson T.M.,Ting L.M.,Zhan C.,Shi W.,Zheng R.,Almo S.C.,Kim K.
Structural determinants of the 5'-methylthioinosine specificity of Plasmodium purine nucleoside phosphorylase.
PLoS ONE
9
0-0
2014
1231200
Ducati R.G.,Namanja-Magliano H.A.,Harijan R.K.,Fajardo J.E.,Fiser A.,Daily J.P.,Schramm V.L.
Genetic resistance to purine nucleoside phosphorylase inhibition in Plasmodium falciparum.
Proc. Natl. Acad. Sci. U.S.A.
115
2114-2119
2018
