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Sequence of FAAH_ARATH

EC Number:3.5.1.99

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
fatty acid amide hydrolase
Q7XJJ7
Arabidopsis thaliana
607
66079
Reaction
anandamide + H2O = arachidonic acid + ethanolamine
Other sequences found for EC No. 3.5.1.99

General information:

Sequence
show sequence in fasta format
  0 MGKYQVMKRA SEVDLSTVKY KAETMKAPHL TGLSFKLFVN LLEAPLIGSL IVDYLKKDNG
 60 MTKIFRNTVI PEEPMFRPEF PSQEPEHDVV IVGEDESPID RLETALKCLP QYDPSRSLHA
120 DPVSSFRYWK IRDYAYAYRS KLTTPLQVAK RIISIIEEFG YDKPPTPFLI RFDANEVIKQ
180 AEASTRRFEQ GNPISVLDGI FVTIKDDIDC LPHPTNGGTT WLHEDRSVEK DSAVVSKLRS
240 CGAILLGKAN MHELGMGTTG NNSNYGTTRN PHDPKRYTGG SSSGSAAIVA AGLCSAALGT
300 DGGGSVRIPS ALCGITGLKT TYGRTDMTGS LCEGGTVEII GPLASSLEDA FLVYAAILGS
360 SSADRYNLKP SPPCFPKLLS HNGSNAIGSL RLGKYTKWFN DVSSSDISDK CEDILKLLSN
420 NHGCKVVEIV VPELEEMRAA HVISIGSPTL SSLTPYCEAG KNSKLSYDTR TSFAIFRSFS
480 ASDYIAAQCL RRRLMEYHLN IFKDVDVIVT PTTGMTAPVI PPDALKNGET NIQVTTDLMR
540 FVLAANLLGF PAISVPVGYD KEGLPIGLQI MGRPWAEATV LGLAAAVEEL APVTKKPAIF
600 YDILNTN
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1185240
Shrestha R.,Dixon R.A.,Chapman K.D.
Molecular identification of a functional homologue of the mammalian fatty acid amide hydrolase in Arabidopsis thaliana.
J. Biol. Chem.
278
34990-34997
2003
1185242
Cheng C.Y.,Krishnakumar V.,Chan A.P.,Thibaud-Nissen F.,Schobel S.,Town C.D.
Araport11: a complete reannotation of the Arabidopsis thaliana reference genome.
Plant J.
89
789-804
2017
1185243
Yamada K.,Lim J.,Dale J.M.,Chen H.,Shinn P.,Palm C.J.,Southwick A.M.,Wu H.C.,Kim C.J.,Nguyen M.,Pham P.K.,Cheuk R.F.,Karlin-Newmann G.,Liu S.X.,Lam B.,Sakano H.,Wu T.,Yu G.,Miranda M.,Quach H.L.,Tripp M.,Chang C.H.,Lee J.M.,Toriumi M.J.,Chan M.M.,Tang C.C.,Onodera C.S.,Deng J.M.,Akiyama K.,Ansari Y.,Arakawa T.,Banh J.,Banno F.,Bowser L.,Brooks S.Y.,Carninci P.,Chao Q.,Choy N.,Enju A.,Goldsmith A.D.,Gurjal M.,Hansen N.F.,Hayashizaki Y.,Johnson-Hopson C.,Hsuan V.W.,Iida K.,Karnes M.,Khan S.,Koesema E.,Ishida J.,Jiang P.X.,Jones T.,Kawai J.,Kamiya A.,Meyers C.,Nakajima M.,Narusaka M.,Seki M.,Sakurai T.,Satou M.,Tamse R.,Vaysberg M.,Wallender E.K.,Wong C.,Yamamura Y.,Yuan S.,Shinozaki K.,Davis R.W.,Theologis A.,Ecker J.R.
Empirical analysis of transcriptional activity in the Arabidopsis genome.
Science
302
842-846
2003
1185244
Shrestha R.,Kim S.C.,Dyer J.M.,Dixon R.A.,Chapman K.D.
Plant fatty acid (ethanol) amide hydrolases.
Biochim. Biophys. Acta
1761
324-334
2006
1185245
Pollmann S.,Neu D.,Lehmann T.,Berkowitz O.,Schaefer T.,Weiler E.W.
Subcellular localization and tissue specific expression of amidase 1 from Arabidopsis thaliana.
Planta
224
1241-1253
2006
1185246
Wang Y.S.,Shrestha R.,Kilaru A.,Wiant W.,Venables B.J.,Chapman K.D.,Blancaflor E.B.
Manipulation of Arabidopsis fatty acid amide hydrolase expression modifies plant growth and sensitivity to N-acylethanolamines.
Proc. Natl. Acad. Sci. U.S.A.
103
12197-12202
2006
1185247
Kang L.,Wang Y.S.,Uppalapati S.R.,Wang K.,Tang Y.,Vadapalli V.,Venables B.J.,Chapman K.D.,Blancaflor E.B.,Mysore K.S.
Overexpression of a fatty acid amide hydrolase compromises innate immunity in Arabidopsis.
Plant J.
56
336-349
2008
1185248
Kim S.C.,Kang L.,Nagaraj S.,Blancaflor E.B.,Mysore K.S.,Chapman K.D.
Mutations in Arabidopsis fatty acid amide hydrolase reveal that catalytic activity influences growth but not sensitivity to abscisic acid or pathogens.
J. Biol. Chem.
284
34065-34074
2009
1185249
Teaster N.D.,Keereetaweep J.,Kilaru A.,Wang Y.S.,Tang Y.,Tran C.N.,Ayre B.G.,Chapman K.D.,Blancaflor E.B.
Overexpression of fatty acid amide hydrolase induces early flowering in Arabidopsis thaliana.
Front. Plant Sci.
3
32-32
2012
1185250
Palmer A.G.,Senechal A.C.,Mukherjee A.,Ane J.M.,Blackwell H.E.
Plant responses to bacterial N-acyl L-homoserine lactones are dependent on enzymatic degradation to L-homoserine.
ACS Chem. Biol.
9
1834-1845
2014
1185251
Khan B.R.,Faure L.,Chapman K.D.,Blancaflor E.B.
A chemical genetic screen uncovers a small molecule enhancer of the N-acylethanolamine degrading enzyme, fatty acid amide hydrolase, in Arabidopsis.
Sci. Rep.
7
41121-41121
2017
1185252
Aziz M.,Wang X.,Tripathi A.,Bankaitis V.A.,Chapman K.D.
Structural analysis of a plant fatty acid amide hydrolase provides insights into the evolutionary diversity of bioactive acylethanolamides.
J. Biol. Chem.
294
7419-7432
2019