Sequence of LEU1_METJA

EC Number:2.3.3.13

2.3.3.13

2-isopropylmalate synthase

Q58595

Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

518

56620

Swiss-Prot

Reaction

acetyl-CoA + 3-methyl-2-oxobutanoate + H2O = (2S)-2-isopropylmalate + CoA

Other sequences found for EC No. 2.3.3.13

General information:

Sequence

0 MIIYREENEI IKKALENLNI PDRVYIFDTT LRDGEQTPGV SLTPEEKIDI AIKLDDLGVD

60 VIEAGFPVSS LGEQEAIKKI CSLNLDAEIC GLARAVKKDI DVAIDCGVDR IHTFIATSPL

120 HRKYKLKKSK EEIIDIAVDA IEYIKEHGIR VEFSAEDATR TEIDYLIEVY KKAVDAGADI

180 INVPDTVGVM IPRAMYYLIN ELKKEIKVPI SVHCHNDFGL AVANSLAAVE AGAEQVHCTI

240 NGLGERGGNA ALEEVVMSLM SIYGVKTNIK TQKLYEISQL VSKYTEIKVQ PNKAIVGENA

300 FAHESGIHAH GVLAHALTYE PIPPELVGQK RKIILGKHTG THAIEAKLKE LGIEVGKDIN

360 KDQFDEIVKR IKALGDKGKR VTDRDVEAIV EDVVGKLAKK DRVVELEQIA VMTGNRVIPT

420 ASVALKIEEE IKKSSAIGVG PVDAAVKAIQ KAIGEKIKLK EYHINAITGG TDALAEVIVT

480 LEGYGREITT KAASEDIVRA SVEAVIDGIN KILAKREK

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Sequence related references

691179

Bult C.J.,White O.,Olsen G.J.,Zhou L.,Fleischmann R.D.,Sutton G.G.,Blake J.A.,FitzGerald L.M.,Clayton R.A.,Gocayne J.D.,Kerlavage A.R.,Dougherty B.A.,Tomb J.-F.,Adams M.D.,Reich C.I.,Overbeek R.,Kirkness E.F.,Weinstock K.G.,Merrick J.M.,Glodek A.,Scott J.L.,Geoghagen N.S.M.,Weidman J.F.,Fuhrmann J.L.,Nguyen D.,Utterback T.R.,Kelley J.M.,Peterson J.D.,Sadow P.W.,Hanna M.C.,Cotton M.D.,Roberts K.M.,Hurst M.A.,Kaine B.P.,Borodovsky M.,Klenk H.-P.,Fraser C.M.,Smith H.O.,Woese C.R.,Venter J.C.

Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii.

Science

273

1058-1073

1996

8688087

691180

Howell D.M.,Harich K.,Xu H.,White R.H.

Alpha-keto acid chain elongation reactions involved in the biosynthesis of coenzyme B (7-mercaptoheptanoyl threonine phosphate) in methanogenic Archaea.

Biochemistry

10108-10117

1998

9665716