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Sequence of SYD_THEKO

EC Number:6.1.1.12

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
aspartate-tRNA ligase
Q52428
Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
438
50910
Reaction
ATP + L-aspartate + tRNAAsp = AMP + diphosphate + L-aspartyl-tRNAAsp
Other sequences found for EC No. 6.1.1.12

General information:

Sequence
show sequence in fasta format
  0 MYRTHYSSEI TEELNGQKVK VAGWVWEVKD LGGIKFLWIR DRDGIVQITA PKKKVDPELF
 60 KLIPKLRSED VVAVEGVVNF TPKAKLGFEI LPEKIVVLNR AETPLPLDPT GKVKAELDTR
120 LDNRFMDLRR PEVMAIFKIR SSVFKAVRDF FHENGFIEIH TPKIIATATE GGTELFPMKY
180 FEEDAFLAQS PQLYKQIMMA SGLDRVYEIA PIFRAEEHNT TRHLNEAWSI DSEMAFIEDE
240 EEVMSFLERL VAHAINYVRE HNAKELDILN FELEEPKLPF PRVSYDKALE ILGDLGKEIP
300 WGEDIDTEGE RLLGKYMMEN ENAPLYFLYQ YPSEAKPFYI MKYDNKPEIC RAFDLEYRGV
360 EISSGGQREH RHDILVEQIK EKGLNPESFE FYLKAFRYGM PPHGGFGLGA ERLIKQMLDL
420 PNIREVILFP RDRRRLTP
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
870551
Imanaka T.,Lee S.,Takagi M.,Fujiwara S.
Aspartyl-tRNA synthetase of the hyperthermophilic archaeon Pyrococcus sp. KOD1 has a chimerical structure of eukaryotic and bacterial enzymes.
Gene
164
153-156
1995
870552
Fukui T.,Atomi H.,Kanai T.,Matsumi R.,Fujiwara S.,Imanaka T.
Complete genome sequence of the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1 and comparison with Pyrococcus genomes.
Genome Res.
15
352-363
2005
870553
Tumbula-Hansen D.,Feng L.,Toogood H.,Stetter K.O.,Soll D.
Evolutionary divergence of the archaeal aspartyl-tRNA synthetases into discriminating and nondiscriminating forms.
J. Biol. Chem.
277
37184-37190
2002
870554
Charron C.,Roy H.,Blaise M.,Giege R.,Kern D.
Non-discriminating and discriminating aspartyl-tRNA synthetases differ in the anticodon-binding domain.
EMBO J.
22
1632-1643
2003
870555
Feng L.,Tumbula-Hansen D.,Toogood H.,Soll D.
Expanding tRNA recognition of a tRNA synthetase by a single amino acid change.
Proc. Natl. Acad. Sci. U.S.A.
100
5676-5681
2003
870556
Schmitt E.,Moulinier L.,Fujiwara S.,Imanaka T.,Thierry J.-C.,Moras D.
Crystal structure of aspartyl-tRNA synthetase from Pyrococcus kodakaraensis KOD: archaeon specificity and catalytic mechanism of adenylate formation.
EMBO J.
17
5227-5237
1998