Sequence of CYSKM_ARATH
EC Number:2.5.1.47
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
O-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate
Other sequences found for EC No. 2.5.1.47
General information:
Sequence
0 MVAMIMASRF NREAKLASQI LSTLLGNRSC YTSMAATSSS ALLLNPLTSS SSSSTLRRFR
60 CSPEISSLSF SSASDFSLAM KRQSRSFADG SERDPSVVCE AVKRETGPDG LNIADNVSQL
120 IGKTPMVYLN SIAKGCVANI AAKLEIMEPC CSVKDRIGYS MVTDAEQKGF ISPGKSVLVE
180 PTSGNTGIGL AFIAASRGYR LILTMPASMS MERRVLLKAF GAELVLTDPA KGMTGAVQKA
240 EEILKNTPDA YMLQQFDNPA NPKIHYETTG PEIWDDTKGK VDIFVAGIGT GGTITGVGRF
300 IKEKNPKTQV IGVEPTESDI LSGGKPGPHK IQGIGAGFIP KNLDQKIMDE VIAISSEEAI
360 ETAKQLALKE GLMVGISSGA AAAAAIKVAK RPENAGKLIA VVFPSFGERY LSTPLFQSIR
420 EEVEKMQPEV
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
532763
Hesse H.,Lipke J.,Altmann T.,Hofgen R.
Molecular cloning and expression analyses of mitochondrial and plastidic isoforms of cysteine synthase (O-acetylserine(thiol)lyase) from Arabidopsis thaliana.
Amino Acids
16
113-131
1999
532764
Salanoubat M.,Lemcke K.,Rieger M.,Ansorge W.,Unseld M.,Fartmann B.,Valle G.,Bloecker H.,Perez-Alonso M.,Obermaier B.,Delseny M.,Boutry M.,Grivell L.A.,Mache R.,Puigdomenech P.,De Simone V.,Choisne N.,Artiguenave F.,Robert C.,Brottier P.,Wincker P.,Cattolico L.,Weissenbach J.,Saurin W.,Quetier F.,Schaefer M.,Mueller-Auer S.,Gabel C.,Fuchs M.,Benes V.,Wurmbach E.,Drzonek H.,Erfle H.,Jordan N.,Bangert S.,Wiedelmann R.,Kranz H.,Voss H.,Holland R.,Brandt P.,Nyakatura G.,Vezzi A.,D'Angelo M.,Pallavicini A.,Toppo S.,Simionati B.,Conrad A.,Hornischer K.,Kauer G.,Loehnert T.-H.,Nordsiek G.,Reichelt J.,Scharfe M.,Schoen O.,Bargues M.,Terol J.,Climent J.,Navarro P.,Collado C.,Perez-Perez A.,Ottenwaelder B.,Duchemin D.,Cooke R.,Laudie M.,Berger-Llauro C.,Purnelle B.,Masuy D.,de Haan M.,Maarse A.C.,Alcaraz J.-P.,Cottet A.,Casacuberta E.,Monfort A.,Argiriou A.,Flores M.,Liguori R.,Vitale D.,Mannhaupt G.,Haase D.,Schoof H.,Rudd S.,Zaccaria P.,Mewes H.-W.,Mayer K.F.X.,Kaul S.,Town C.D.,Koo H.L.,Tallon L.J.,Jenkins J.,Rooney T.,Rizzo M.,Walts A.,Utterback T.,Fujii C.Y.,Shea T.P.,Creasy T.H.,Haas B.,Maiti R.,Wu D.,Peterson J.,Van Aken S.,Pai G.,Militscher J.,Sellers P.,Gill J.E.,Feldblyum T.V.,Preuss D.,Lin X.,Nierman W.C.,Salzberg S.L.,White O.,Venter J.C.,Fraser C.M.,Kaneko T.,Nakamura Y.,Sato S.,Kato T.,Asamizu E.,Sasamoto S.,Kimura T.,Idesawa K.,Kawashima K.,Kishida Y.,Kiyokawa C.,Kohara M.,Matsumoto M.,Matsuno A.,Muraki A.,Nakayama S.,Nakazaki N.,Shinpo S.,Takeuchi C.,Wada T.,Watanabe A.,Yamada M.,Yasuda M.,Tabata S.
Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.
Nature
408
820-822
2000
532765
Cheng C.Y.,Krishnakumar V.,Chan A.P.,Thibaud-Nissen F.,Schobel S.,Town C.D.
Araport11: a complete reannotation of the Arabidopsis thaliana reference genome.
Plant J.
89
789-804
2017
532766
Yamada K.,Lim J.,Dale J.M.,Chen H.,Shinn P.,Palm C.J.,Southwick A.M.,Wu H.C.,Kim C.J.,Nguyen M.,Pham P.K.,Cheuk R.F.,Karlin-Newmann G.,Liu S.X.,Lam B.,Sakano H.,Wu T.,Yu G.,Miranda M.,Quach H.L.,Tripp M.,Chang C.H.,Lee J.M.,Toriumi M.J.,Chan M.M.,Tang C.C.,Onodera C.S.,Deng J.M.,Akiyama K.,Ansari Y.,Arakawa T.,Banh J.,Banno F.,Bowser L.,Brooks S.Y.,Carninci P.,Chao Q.,Choy N.,Enju A.,Goldsmith A.D.,Gurjal M.,Hansen N.F.,Hayashizaki Y.,Johnson-Hopson C.,Hsuan V.W.,Iida K.,Karnes M.,Khan S.,Koesema E.,Ishida J.,Jiang P.X.,Jones T.,Kawai J.,Kamiya A.,Meyers C.,Nakajima M.,Narusaka M.,Seki M.,Sakurai T.,Satou M.,Tamse R.,Vaysberg M.,Wallender E.K.,Wong C.,Yamamura Y.,Yuan S.,Shinozaki K.,Davis R.W.,Theologis A.,Ecker J.R.
Empirical analysis of transcriptional activity in the Arabidopsis genome.
Science
302
842-846
2003
532767
Jost R.,Berkowitz O.,Wirtz M.,Hopkins L.,Hawkesford M.J.,Hell R.
Genomic and functional characterization of the oas gene family encoding O-acetylserine (thiol) lyases, enzymes catalyzing the final step in cysteine biosynthesis in Arabidopsis thaliana.
Gene
253
237-247
2000
532768
Hatzfeld Y.,Maruyama A.,Schmidt A.,Noji M.,Ishizawa K.,Saito K.
beta-Cyanoalanine synthase is a mitochondrial cysteine synthase-like protein in spinach and Arabidopsis.
Plant Physiol.
123
1163-1171
2000
532769
Wirtz M.,Droux M.,Hell R.
O-acetylserine (thiol) lyase: an enigmatic enzyme of plant cysteine biosynthesis revisited in Arabidopsis thaliana.
J. Exp. Bot.
55
1785-1798
2004
532770
Heazlewood J.L.,Tonti-Filippini J.S.,Gout A.M.,Day D.A.,Whelan J.,Millar A.H.
Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.
Plant Cell
16
241-256
2004
532771
Wirtz M.,Droux M.
Synthesis of the sulfur amino acids: cysteine and methionine.
Photosyn. Res.
86
345-362
2005
532772
Heeg C.,Kruse C.,Jost R.,Gutensohn M.,Ruppert T.,Wirtz M.,Hell R.
Analysis of the Arabidopsis O-acetylserine(thiol)lyase gene family demonstrates compartment-specific differences in the regulation of cysteine synthesis.
Plant Cell
20
168-185
2008
532773
Watanabe M.,Kusano M.,Oikawa A.,Fukushima A.,Noji M.,Saito K.
Physiological roles of the beta-substituted alanine synthase gene family in Arabidopsis.
Plant Physiol.
146
310-320
2008
532774
Feldman-Salit A.,Wirtz M.,Hell R.,Wade R.C.
A mechanistic model of the cysteine synthase complex.
J. Mol. Biol.
386
37-59
2009
532775
Wirtz M.,Heeg C.,Samami A.A.,Ruppert T.,Hell R.
Enzymes of cysteine synthesis show extensive and conserved modifications patterns that include N(alpha)-terminal acetylation.
Amino Acids
39
1077-1086
2010
532776
Wirtz M.,Birke H.,Heeg C.,Mueller C.,Hosp F.,Throm C.,Koenig S.,Feldman-Salit A.,Rippe K.,Petersen G.,Wade R.C.,Rybin V.,Scheffzek K.,Hell R.
Structure and function of the hetero-oligomeric cysteine synthase complex in plants.
J. Biol. Chem.
285
32810-32817
2010
532777
Wirtz M.,Beard K.F.,Lee C.P.,Boltz A.,Schwarzlaender M.,Fuchs C.,Meyer A.J.,Heeg C.,Sweetlove L.J.,Ratcliffe R.G.,Hell R.
Mitochondrial cysteine synthase complex regulates O-acetylserine biosynthesis in plants.
J. Biol. Chem.
287
27941-27947
2012
532778
Alvarez C.,Garcia I.,Romero L.C.,Gotor C.
Mitochondrial sulfide detoxification requires a functional isoform O-acetylserine(thiol)lyase C in Arabidopsis thaliana.
Mol. Plant
5
1217-1226
2012
532779
Wawrzynska A.,Kurzyk A.,Mierzwinska M.,Plochocka D.,Wieczorek G.,Sirko A.
Direct targeting of Arabidopsis cysteine synthase complexes with synthetic polypeptides to selectively deregulate cysteine synthesis.
Plant Sci.
207
148-157
2013
532780
Carrie C.,Venne A.S.,Zahedi R.P.,Soll J.
Identification of cleavage sites and substrate proteins for two mitochondrial intermediate peptidases in Arabidopsis thaliana.
J. Exp. Bot.
66
2691-2708
2015
