Sequence of NADC_HUMAN
EC Number:2.4.2.19
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
beta-nicotinate D-ribonucleotide + diphosphate + CO2 = pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
Other sequences found for EC No. 2.4.2.19
General information:
Sequence
0 MDAEGLALLL PPVTLAALVD SWLREDCPGL NYAALVSGAG PSQAALWAKS PGVLAGQPFF
60 DAIFTQLNCQ VSWFLPEGSK LVPVARVAEV RGPAHCLLLG ERVALNTLAR CSGIASAAAA
120 AVEAARGAGW TGHVAGTRKT TPGFRLVEKY GLLVGGAASH RYDLGGLVMV KDNHVVAAGG
180 VEKAVRAARQ AADFTLKVEV ECSSLQEAVQ AAEAGADLVL LDNFKPEELH PTATVLKAQF
240 PSVAVEASGG ITLDNLPQFC GPHIDVISMG MLTQAAPALD FSLKLFAKEV APVPKIH
Download this sequence
in fasta formatDownload all sequences for 2.4.2.19
in fasta format
in csv (Excel, OpenOffice) formatSequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1218285
Fukuoka S.,Nyaruhucha C.M.,Shibata K.
Characterization and functional expression of the cDNA encoding human brain quinolinate phosphoribosyltransferase.
Biochim. Biophys. Acta
1395
192-201
1998
1218287
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
1218288
Bian Y.,Song C.,Cheng K.,Dong M.,Wang F.,Huang J.,Sun D.,Wang L.,Ye M.,Zou H.
An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
J. Proteomics
96
253-262
2014
1218289
Liu H.,Woznica K.,Catton G.,Crawford A.,Botting N.,Naismith J.H.
Structural and kinetic characterization of quinolinate phosphoribosyltransferase (hQPRTase) from homo sapiens.
J. Mol. Biol.
373
755-763
2007
1218290
Malik S.S.,Patterson D.N.,Ncube Z.,Toth E.A.
The crystal structure of human quinolinic acid phosphoribosyltransferase in complex with its inhibitor phthalic acid.
Proteins
82
405-414
2014
1218291
Youn H.S.,Kim T.G.,Kim M.K.,Kang G.B.,Kang J.Y.,Lee J.G.,An J.Y.,Park K.R.,Lee Y.,Im Y.J.,Lee J.H.,Eom S.H.
Structural Insights into the Quaternary Catalytic Mechanism of Hexameric Human Quinolinate Phosphoribosyltransferase, a Key Enzyme in de novo NAD Biosynthesis.
Sci. Rep.
6
19681-19681
2016
1218292
Burkard T.R.,Planyavsky M.,Kaupe I.,Breitwieser F.P.,Buerckstuemmer T.,Bennett K.L.,Superti-Furga G.,Colinge J.
Initial characterization of the human central proteome.
BMC Syst. Biol.
5
17-17
2011
