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Sequence of T23O_CAEEL

EC Number:1.13.11.11

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
tryptophan 2,3-dioxygenase
Q09474
Caenorhabditis elegans
403
46716
Reaction
L-tryptophan + O2 = N-formyl-L-kynurenine
Other sequences found for EC No. 1.13.11.11

General information:

Sequence
show sequence in fasta format
  0 MACPYLGSGE LTHRVTFMEG GEECQQGVNK VEMGFGQTYS EYLQLDKILT AQRLKSEADG
 60 QRVDDEHLFI VIHQAHELWF KQIIFDLDNV RKLLNNTIVD ETKTLKIVSG LDRMTKILSL
120 LTEQITLLDT MSPLDFVDFR KYLTPASGFQ SLQFRVLENK LGVRQERRIK YNAQHYKNVF
180 NDTDLKTLNV TEEEKSLLTL IESWLERTPG LKSTSEDEGF WIKYEKSVNK YLADLAKQAA
240 DPSNTEEIAK QLTAEYHKTA DAFQSILDPR QHEQHIRNGN RLLSHDATKG AMMIYFYRDM
300 PRFSQPYQIL TFLMDIDSLF TKWRYNHVLL VQRMLGAKQG TGGSSGYMYL RSTVSDRYKV
360 FLDLFNLSTW LIPREYIPML SPRMVKTLSE HSNLSHSQSS ESD
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
617539
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science
282
2012-2018
1998
617540
van der Goot A.T.,Zhu W.,Vazquez-Manrique R.P.,Seinstra R.I.,Dettmer K.,Michels H.,Farina F.,Krijnen J.,Melki R.,Buijsman R.C.,Ruiz Silva M.,Thijssen K.L.,Kema I.P.,Neri C.,Oefner P.J.,Nollen E.A.
Delaying aging and the aging-associated decline in protein homeostasis by inhibition of tryptophan degradation.
Proc. Natl. Acad. Sci. U.S.A.
109
14912-14917
2012
617541
Michels H.,Seinstra R.I.,Uitdehaag J.C.,Koopman M.,van Faassen M.,Martineau C.N.,Kema I.P.,Buijsman R.,Nollen E.A.
Identification of an evolutionary conserved structural loop that is required for the enzymatic and biological function of tryptophan 2,3-dioxygenase.
Sci. Rep.
6
39199-39199
2016